Biochemistry and Molecular Biology

Publications 1981 2018

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2018

XEN and the Art of Stem Cell Maintenance: Molecular Mechanisms Maintaining Cell Fate and Self-Renewal in Extraembryonic Endoderm Stem (XEN) Cell Lines

Ralston, A. Jan 1 2018 Advances in Anatomy Embryology and Cell Biology. Springer Verlag, Vol. 229, p. 69-78 10 p. (Advances in Anatomy Embryology and Cell Biology; vol. 229)

Research output: ResearchChapter

Endoderm
Art
Stem Cells
Maintenance
Cell Line
2016
2 Citations

Biolayer interferometry: A novel method to Elucidate Protein-Protein and Protein-DNA interactions in the Mitochondrial DNA Replisome

Ciesielski, G. L., Hytönen, V. P. & Kaguni, L. S. 2016 Methods in Molecular Biology. Humana Press Inc., Vol. 1351, p. 223-231 9 p. (Methods in Molecular Biology; vol. 1351)

Research output: ResearchChapter

Interferometry
Mitochondrial Diseases
Mitochondrial DNA
DNA
Proteins

Expression and purification of mitochondrial RNA polymerase and transcription factor a from drosophila melanogaster

Gajewski, J. P., Arnold, J. J., Salminen, T. S., Kaguni, L. S. & Cameron, C. E. 2016 Methods in Molecular Biology. Humana Press Inc., Vol. 1351, p. 199-210 12 p. (Methods in Molecular Biology; vol. 1351)

Research output: ResearchChapter

DNA-Directed RNA Polymerases
Drosophila melanogaster
Transcription Factors
Proteins
mitochondrial RNA
1 Citations

Purification and Comparative assay of Human Mitochondrial single-stranded DNA-binding protein

Ciesielski, G. L., Rosado-Ruiz, F. A. & Kaguni, L. S. 2016 Methods in Molecular Biology. Humana Press Inc., Vol. 1351, p. 211-222 12 p. (Methods in Molecular Biology; vol. 1351)

Research output: ResearchChapter

Mitochondrial DNA
human SSBP1 protein
DNA-Binding Proteins
DNA Helicases
Single-Stranded DNA

Purification and comparative assay of the human mitochondrial replicative DNA helicase

Rosado-Ruiz, F. A., So, M. & Kaguni, L. S. 2016 Methods in Molecular Biology. Humana Press Inc., Vol. 1351, p. 185-198 14 p. (Methods in Molecular Biology; vol. 1351)

Research output: ResearchChapter

DNA Helicases
Mitochondrial DNA
Enzymes
Enzyme Stability
Mitochondrial Genome
2013
3 Citations

SiRNA therapeutic design: Tools and challenges

Malefyt, A. P., Angart, P. A., Chan, C. & Walton, S. P. Aug 1 2013 Regulatory RNAs: Basics, Methods and Applications. Springer-Verlag Berlin Heidelberg, p. 475-503 29 p.

Research output: ResearchChapter

RNA Interference
Therapeutics
RNA
Small Interfering RNA
Clinical Trials