Profile The profile is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 9 Similar Profiles
Adenoviridae Medicine & Life Sciences
Genes Medicine & Life Sciences
Glycogen Storage Disease Type II Medicine & Life Sciences
Genetic Therapy Medicine & Life Sciences
Vaccines Medicine & Life Sciences
Innate Immunity Medicine & Life Sciences
Proteins Medicine & Life Sciences
Liver Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2005 2017

Publications 1990 2017

Current and Future Treatments for Lysosomal Storage Disorders

Rastall, D. P. W. & Amalfitano, A. Dec 1 2017 In : Current Treatment Options in Neurology. 19, 12, 45

Research output: Research - peer-reviewReview article

Therapeutics
Genetic Therapy
Hematopoietic Stem Cells
Transplants
Clinical Trials

Decreased vector gene expression from e2b gene-deleted adenovirus serotype 5 vaccines intensifies proinflammatory immune responses

Quiroga, D., Aldhamen, Y. A., Godbehere, S., Harding, L. & Amalfitano, A. Jun 1 2017 In : Clinical and Vaccine Immunology. 24, 6, e00061-17

Research output: Research - peer-reviewArticle

Adenoviridae
Vaccines
Gene Expression
Genes
Serogroup

Mice expressing human ERAP1 variants associated with ankylosing spondylitis have altered T-cell repertoires and NK cell functions, as well as increased in utero and perinatal mortality

Rastall, D. P. W., Alyaquob, F. S., O'Connell, P., Pepelyayeva, Y., Peters, D., Godbehere-Roosa, S., Pereira-Hicks, C., Aldhamen, Y. A. & Amalfitano, A. Jun 1 2017 In : International Immunology. 29, 6, p. 277-289 13 p.

Research output: Research - peer-reviewArticle

Aminopeptidases
Perinatal Mortality
Ankylosing Spondylitis
Natural Killer Cells
Endoplasmic Reticulum
2 Citations

In vivo synthesis of cyclic-di-GMP using a recombinant adenovirus preferentially improves adaptive immune responses against extracellular antigens

Alyaqoub, F. S., Aldhamen, Y. A., Koestler, B. J., Bruger, E. L., Seregin, S. S., Pereira-Hicks, C., Godbehere, S., Waters, C. M. & Amalfitano, A. Feb 15 2016 In : Journal of Immunology. 196, 4, p. 1741-1752 12 p.

Research output: Research - peer-reviewArticle

Cyclic GMP
Adaptive Immunity
Adenoviridae
Antigens
bis(3',5')-cyclic diguanylic acid
4 Citations

Long-term, high-level hepatic secretion of acid α-glucosidase for Pompe disease achieved in non-human primates using helper-dependent adenovirus

Rastall, D. P. W., Seregin, S. S., Aldhamen, Y. A., Kaiser, L. M., Mullins, C., Liou, A., Ing, F., Pereria-Hicks, C., Godbehere-Roosa, S., Palmer, D., Ng, P. & Amalfitano, A. Jul 21 2016 (Accepted/In press) In : Gene Therapy.

Research output: Research - peer-reviewArticle

Glycogen Storage Disease Type II
alpha-Glucosidases
Adenoviridae
Primates
Acids