Profile The profile is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 8 Similar Profiles
Adenoviridae Medicine & Life Sciences
Genes Medicine & Life Sciences
Vaccines Medicine & Life Sciences
Glycogen Storage Disease Type II Medicine & Life Sciences
Genetic Therapy Medicine & Life Sciences
Innate Immunity Medicine & Life Sciences
Proteins Medicine & Life Sciences
Liver Medicine & Life Sciences

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Grants 2005 2017

Publications 1990 2017

Decreased vector gene expression from e2b gene-deleted adenovirus serotype 5 vaccines intensifies proinflammatory immune responses

Quiroga, D., Aldhamen, Y. A., Godbehere, S., Harding, L. & Amalfitano, A. Jun 1 2017 In : Clinical and Vaccine Immunology. 24, 6, e00061-17

Research output: Contribution to journalArticle

Adenoviridae
Vaccines
Gene Expression
Genes
Serogroup
2 Citations

In vivo synthesis of cyclic-di-GMP using a recombinant adenovirus preferentially improves adaptive immune responses against extracellular antigens

Alyaqoub, F. S., Aldhamen, Y. A., Koestler, B. J., Bruger, E. L., Seregin, S. S., Pereira-Hicks, C., Godbehere, S., Waters, C. M. & Amalfitano, A. Feb 15 2016 In : Journal of Immunology. 196, 4, p. 1741-1752 12 p.

Research output: Contribution to journalArticle

Cyclic GMP
Adaptive Immunity
Adenoviridae
Antigens
Vaccines
2 Citations

Long-term, high-level hepatic secretion of acid α-glucosidase for Pompe disease achieved in non-human primates using helper-dependent adenovirus

Rastall, D. P. W., Seregin, S. S., Aldhamen, Y. A., Kaiser, L. M., Mullins, C., Liou, A., Ing, F., Pereria-Hicks, C., Godbehere-Roosa, S., Palmer, D., Ng, P. & Amalfitano, A. Jul 21 2016 In : Gene Therapy.

Research output: Contribution to journalArticle

Glycogen Storage Disease Type II
alpha-Glucosidases
Adenoviridae
Primates
Acids

Methods to Mitigate Immune Responses to Adenoviral Vectors

Aldhamen, Y. A. & Amalfitano, A. Apr 6 2016 Adenoviral Vectors for Gene Therapy: Second Edition. Elsevier Inc., p. 391-422 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Adenoviridae
Galantamine
Gene transfer
Genetic Therapy
Genes
6 Citations

Autoimmune disease-associated variants of extracellular endoplasmic reticulum aminopeptidase 1 induce altered innate immune responses by human immune cells

Aldhamen, Y. A., Pepelyayeva, Y., Rastall, D. P. W., Seregin, S. S., Zervoudi, E., Koumantou, D., Aylsworth, C. F., Quiroga, D., Godbehere, S., Georgiadis, D., Stratikos, E. & Amalfitano, A. May 6 2015 In : Journal of Innate Immunity. 7, 3, p. 275-289 15 p.

Research output: Contribution to journalArticle

Aminopeptidases
Innate Immunity
Endoplasmic Reticulum
Autoimmune Diseases
Blood Cells