Profile The profile is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Grants 2009 2019

Publications 1990 2017

Alpha-Synuclein mRNA Is Not Increased

Su, X., Fischer, D. L., Li, X., Bankiewicz, K., Sortwell, C. E. & Federoff, H. J. 2017 (Accepted/In press) In : Molecular Therapy.

Research output: Research - peer-reviewArticle

Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form

Collier, T. J., Srivastava, K. R., Justman, C., Grammatopoulous, T., Hutter-Paier, B., Prokesch, M., Havas, D., Rochet, J. C., Liu, F., Jock, K., de Oliveira, P., Stirtz, G. L., Dettmer, U., Sortwell, C. E., Feany, M. B., Lansbury, P., Lapidus, L. & Paumier, K. L. Oct 1 2017 In : Neurobiology of Disease. 106, p. 191-204 14 p.

Research output: Research - peer-reviewArticle

Nortriptyline
alpha-Synuclein
Pathology
Protein Conformation
Tricyclic Antidepressive Agents

Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS

Kanaan, N. M., Sellnow, R. C., Boye, S. L., Coberly, B., Bennett, A., Agbandje-McKenna, M., Sortwell, C. E., Hauswirth, W. W., Boye, S. E. & Manfredsson, F. P. Sep 15 2017 In : Molecular Therapy - Nucleic Acids. 8, p. 184-197 14 p.

Research output: Research - peer-reviewArticle

Dependovirus
Capsid
Tyrosine
Heparitin Sulfate
Transgenes

Subthalamic nucleus deep brain stimulation employs trkB signaling for neuroprotection and functional restoration

Fischer, D. L., Kemp, C. J., Cole-Strauss, A., Polinski, N. K., Paumier, K. L., Lipton, J. W., Steece-Collier, K., Collier, T. J., Buhlinger, D. J. & Sortwell, C. E. 2017 In : Journal of Neuroscience. 37, 28, p. 6786-6796 11 p.

Research output: Research - peer-reviewArticle

Subthalamic Nucleus
Deep Brain Stimulation
tropomyosin kinase
Neuroprotection
Substantia Nigra
1 Citations

Impact of age and vector construct on striatal and nigral transgene expression

Polinski, N. K., Manfredsson, F. P., Benskey, M. J., Fischer, D. L., Kemp, C. J., Steece-Collier, K., Sandoval, I. M., Paumier, K. L. & Sortwell, C. E. Mar 16 2016 In : Molecular Therapy - Methods and Clinical Development. 3, p. 16082 1 p.

Research output: Research - peer-reviewArticle

Corpus Striatum
Substantia Nigra
Green Fluorescent Proteins
Transgenes
Lentivirus