Profile The profile is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Grants 2009 2019

Publications 1990 2017

Alpha-Synuclein mRNA Is Not Increased

Su, X., Fischer, D. L., Li, X., Bankiewicz, K., Sortwell, C. E. & Federoff, H. J. 2017 In : Molecular Therapy.

Research output: Contribution to journalArticle

Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form

Collier, T. J., Srivastava, K. R., Justman, C., Grammatopoulous, T., Hutter-Paier, B., Prokesch, M., Havas, D., Rochet, J. C., Liu, F., Jock, K., de Oliveira, P., Stirtz, G. L., Dettmer, U., Sortwell, C. E., Feany, M. B., Lansbury, P., Lapidus, L. & Paumier, K. L. Oct 1 2017 In : Neurobiology of Disease. 106, p. 191-204 14 p.

Research output: Contribution to journalArticle

Nortriptyline
alpha-Synuclein
Pathology
Protein Conformation
Tricyclic Antidepressive Agents

Subthalamic nucleus deep brain stimulation employs trkB signaling for neuroprotection and functional restoration

Fischer, D. L., Kemp, C. J., Cole-Strauss, A., Polinski, N. K., Paumier, K. L., Lipton, J. W., Steece-Collier, K., Collier, T. J., Buhlinger, D. J. & Sortwell, C. E. 2017 In : Journal of Neuroscience. 37, 28, p. 6786-6796 11 p.

Research output: Contribution to journalArticle

Subthalamic Nucleus
Tropomyosin
Deep Brain Stimulation
Phosphotransferases
Substantia Nigra

Impact of age and vector construct on striatal and nigral transgene expression

Polinski, N. K., Manfredsson, F. P., Benskey, M. J., Fischer, D. L., Kemp, C. J., Steece-Collier, K., Sandoval, I. M., Paumier, K. L. & Sortwell, C. E. Mar 16 2016 In : Molecular Therapy - Methods and Clinical Development. 3, p. 16082 1 p.

Research output: Contribution to journalArticle

Corpus Striatum
Substantia Nigra
Green Fluorescent Proteins
Transgenes
Lentivirus
4 Citations

Viral vector-based modeling of neurodegenerative disorders: Parkinson’s disease

Fischer, D. L., Gombash, S. E., Kemp, C. J., Manfredsson, F. P., Polinski, N. K., Duffy, M. F. & Sortwell, C. E. 2016 Methods in Molecular Biology. Humana Press Inc., Vol. 1382, p. 367-382 16 p. (Methods in Molecular Biology; vol. 1382)

Research output: Chapter in Book/Report/Conference proceedingChapter

Neurodegenerative Diseases
Parkinson Disease
Dependovirus
Lentivirus
Genetic Therapy