Publications 2001 2017

  • 26 h-Index
  • 65 Article
  • 2 Chapter
  • 1 Review article
2017

A bioluminescent Pseudomonas aeruginosa wound model reveals increased mortality of type 1 diabetic mice to biofilm infection

Agostinho Hunt, A. M., Gibson, J. A., Larrivee, C. L., O'Reilly, S., Navitskaya, S., Needle, D. B., Abramovitch, R. B., Busik, J. V. & Waters, C. M. Jul 1 2017 In : Journal of Wound Care. 26, 7, p. S24-S33

Research output: Research - peer-reviewArticle

Biofilms
Pseudomonas aeruginosa
Mortality
Wounds and Injuries
Infection

Come to the light side: In vivo monitoring of Pseudomonas aeruginosa biofilm infections in chronic wounds in a diabetic hairless murine model

Agostinho Hunt, A. M., Gibson, J. A., Larrivee, C. L., O’Reilly, S., Navitskaya, S., Busik, J. V. & Waters, C. M. Oct 10 2017 In : Journal of Visualized Experiments. 2017, 128, e55991

Research output: Research - peer-reviewArticle

Biofilms
Pseudomonas aeruginosa
Light
Wounds and Injuries
Infection

Cyclic Di-GMP and VpsR induce the expression of type II secretion in vibrio cholerae

Sloup, R. E., Konal, A. E., Severin, G. B., Korir, M. L., Bagdasarian, M. M., Bagdasarian, M. & Waters, C. M. 2017 In : Journal of Bacteriology. 199, 19, e00106-17

Research output: Research - peer-reviewArticle

Vibrio cholerae
Proteins
bis(3',5')-cyclic diguanylic acid
Operon
Biofilms

Enhancing multiplex genome editing by natural transformation (MuGENT) via inactivation of ssDNA exonucleases

Dalia, T. N., Yoon, S. H., Galli, E., Barre, F. X., Waters, C. M. & Dalia, A. B. Jul 1 2017 In : Nucleic Acids Research. 45, 12, p. 7527-7537 11 p.

Research output: Research - peer-reviewArticle

Exonucleases
Gene Editing
Genome
Vibrio cholerae
Acinetobacter

Resource abundance and the critical transition to cooperation

Connelly, B. D., Bruger, E. L., McKinley, P. K. & Waters, C. M. Apr 1 2017 In : Journal of Evolutionary Biology. 30, 4, p. 750-761 12 p.

Research output: Research - peer-reviewArticle

resource
co-operation
cost
cholera
environmental change

Spectrophotometric and mass spectroscopic methods for the quantification and kinetic evaluation of in vitro c-di-GMP synthesis

Severin, G. B. & Waters, C. M. 2017 Methods in Molecular Biology. Humana Press Inc., Vol. 1657, p. 71-84 14 p. (Methods in Molecular Biology; vol. 1657)

Research output: ResearchChapter

diguanylate cyclase
In Vitro Techniques
Phosphoric Diester Hydrolases
Enzymes
Second Messenger Systems
1 Citations

Spermine inhibits Vibrio cholerae biofilm formation through the NspS–MbaA polyamine signaling system

Sobe, R. C., Bond, W. G., Wotanis, C. K., Zayner, J. P., Burriss, M. A., Fernandez, N., Bruger, E. L., Waters, C. M., Neufeld, H. S. & Karatan, E. 2017 In : Journal of Biological Chemistry. 292, 41, p. 17025-17036 12 p.

Research output: Research - peer-reviewArticle

Vibrio cholerae
Spermine
Polyamines
Biofilms
Spermidine

The proline variant of the W[F/L/M][T/S]R cyclic Di-GMP binding motif suppresses dependence on signal association for regulator function

Chodur, D. M., Guo, L., Pu, M., Bruger, E., Fernandez, N., Waters, C. & Rowe-Magnus, D. A. Jan 1 2017 In : Journal of Bacteriology. 199, 19, e00344-17

Research output: Research - peer-reviewArticle

Proline
bis(3',5')-cyclic diguanylic acid
Vibrio vulnificus
Vibrio parahaemolyticus
Ostreidae
2016
3 Citations

Bacterial quorum sensing stabilizes cooperation by optimizing growth strategies

Bruger, E. L. & Waters, C. M. 2016 In : Applied and Environmental Microbiology. 82, 22, p. 6498-6506 9 p.

Research output: Research - peer-reviewArticle

communication
co-operation
Quorum Sensing
Growth
quorum sensing

Contextual organismality: Beyond pattern to process in the emergence of organisms

Díaz-Muñoz, S. L., Boddy, A. M., Dantas, G., Waters, C. M. & Bronstein, J. L. Dec 1 2016 In : Evolution. 70, 12, p. 2669-2677 9 p.

Research output: Research - peer-reviewArticle

Symbiosis
Neoplasms
Conflict (Psychology)
eclosion
organisms
2 Citations

Cyclic di-AMP released from Staphylococcus aureus biofilm induces a macrophage type I interferon response

Gries, C. M., Bruger, E. L., Moormeier, D. E., Scherr, T. D., Waters, C. M. & Kielian, T. 2016 In : Infection and Immunity. 84, 12, p. 3564-3574 11 p.

Research output: Research - peer-reviewArticle

Interferon Type I
Biofilms
Cyclic AMP
Staphylococcus aureus
Macrophages
3 Citations

Evolution of ecological diversity in biofilms of Pseudomonas aeruginosa by altered cyclic diguanylate signaling

Flynn, K. M., Dowell, G., Johnson, T. M., Koestler, B. J., Waters, C. M. & Cooper, V. S. 2016 In : Journal of Bacteriology. 198, 19, p. 2608-2618 11 p.

Research output: Research - peer-reviewArticle

Biofilms
Pseudomonas aeruginosa
Population
bis(3',5')-cyclic diguanylic acid
DNA Mismatch Repair
2 Citations

In vivo synthesis of cyclic-di-GMP using a recombinant adenovirus preferentially improves adaptive immune responses against extracellular antigens

Alyaqoub, F. S., Aldhamen, Y. A., Koestler, B. J., Bruger, E. L., Seregin, S. S., Pereira-Hicks, C., Godbehere, S., Waters, C. M. & Amalfitano, A. Feb 15 2016 In : Journal of Immunology. 196, 4, p. 1741-1752 12 p.

Research output: Research - peer-reviewArticle

Cyclic GMP
Adaptive Immunity
Adenoviridae
Antigens
bis(3',5')-cyclic diguanylic acid
2 Citations

Polysorbates prevent biofilm formation and pathogenesis of Escherichia coli O104: H4

Sloup, R. E., Cieza, R. J., Needle, D. B., Abramovitch, R. B., Torres, A. G. & Waters, C. M. Aug 18 2016 In : Biofouling. 32, 9, p. 1131-1140 10 p.

Research output: Research - peer-reviewArticle

biofilm
pathogenesis
Escherichia coli
polysorbates
Polysorbates
5 Citations
Biofilms
Buoyancy
Cyanobacteria
bis(3',5')-cyclic diguanylic acid
Synechocystis
1 Citations

Spermidine inversely influences surface interactions and planktonic growth in Agrobacterium tumefaciens

Wang, Y., Kim, S. H., Natarajan, R., Heindl, J. E., Bruger, E. L., Waters, C. M., Michael, A. J. & Fuqua, C. 2016 In : Journal of Bacteriology. 198, 19, p. 2682-2691 10 p.

Research output: Research - peer-reviewArticle

Agrobacterium tumefaciens
Spermidine
Growth
carboxyspermidine
Biofilms
2015
13 Citations

A pterin-dependent signaling pathway regulates a dual-function diguanylate cyclase-phosphodiesterase controlling surface attachment in Agrobacterium tumefaciens

Feirer, N., Xu, J., Allen, K. D., Koestler, B. J., Bruger, E. L., Waters, C. M., White, R. H. & Fuqua, C. Jun 30 2015 In : mBio. 6, 4, e00156-15

Research output: Research - peer-reviewArticle

Pterins
Agrobacterium tumefaciens
Phosphoric Diester Hydrolases
Biofilms
diguanylate cyclase
6 Citations

Cross-talk between a regulatory small RNA, cyclic-di-GMP signalling and flagellar regulator FlhDC for virulence and bacterial behaviours

Yuan, X., Khokhani, D., Wu, X., Yang, F., Biener, G., Koestler, B. J., Raicu, V., He, C., Waters, C. M., Sundin, G. W., Tian, F. & Yang, C. H. Nov 1 2015 In : Environmental Microbiology. 17, 11, p. 4745-4763 19 p.

Research output: Research - peer-reviewArticle

Virulence
RNA
bis(3',5')-cyclic diguanylic acid
virulence
type III secretion system
3 Citations

Intestinal GPS: Bile and bicarbonate control cyclic di-GMP to provide Vibrio cholerae spatial cues within the small intestine

Koestler, B. J. & Waters, C. M. Jan 26 2015 In : Gut Microbes. 5, 6, p. 775-780 6 p.

Research output: Research - peer-reviewArticle

Vibrio cholerae
Bicarbonates
Bile
Small Intestine
Cues
2 Citations

Intracellular concentrations of Borrelia burgdorferi cyclic di-AMP are not changed by altered expression of the CdaA synthase

Savage, C. R., Arnold, W. K., Gjevre-Nail, A., Koestler, B. J., Bruger, E. L., Barker, J. R., Waters, C. M. & Stevenson, B. Apr 23 2015 In : PLoS One. 10, 4, e0125440

Research output: Research - peer-reviewArticle

Adenosine Monophosphate
Cells
Borrelia burgdorferi
Cyclic AMP
Interferon Type I
33 Citations

Oligoribonuclease is the primary degradative enzyme for pGpG in Pseudomonas aeruginosa that is required for cyclic-di-GMP turnover

Orr, M. W., Donaldson, G. P., Severin, G. B., Wang, J., Sintim, H. O., Waters, C. M. & Lee, V. T. Sep 8 2015 In : Proceedings of the National Academy of Sciences of the United States of America. 112, 36, p. E5048-E5057

Research output: Research - peer-reviewArticle

Pseudomonas aeruginosa
Enzymes
oligoribonuclease
bis(3',5')-cyclic diguanylic acid
Biofilms
5 Citations

Sharing the sandbox: Evolutionary mechanisms that maintain bacterial cooperation

Waters, C. & Bruger, E. 2015 In : F1000Research. 4, 1504

Research output: Research - peer-reviewReview article

Biofilms
Sorting
Cooperative Behavior
4 Citations

The cyclic di-GMP phosphodiesterase gene Rv1357c/BCG1419c affects BCG Pellicle production and in Vivo maintenance

Flores-Valdez, M. A., De Jesús Aceves-Sánchez, M., Pedroza-Roldán, C., Vega-Domínguez, P. J., Prado-Montes De Oca, E., Bravo-Madrigal, J., Laval, F., Daffé, M., Koestler, B. & Waters, C. M. Feb 1 2015 In : IUBMB Life. 67, 2, p. 129-138 10 p.

Research output: Research - peer-reviewArticle

Phosphoric Diester Hydrolases
Biofilms
Mycobacterium bovis
Maintenance
Infection
8 Citations

The Yersinia pestisHmsCDE regulatory system is essential for blockage of the oriental rat flea (Xenopsylla cheopis), a classic plague vector

Bobrov, A. G., Kirillina, O., Vadyvaloo, V., Koestler, B. J., Hinz, A. K., Mack, D., Waters, C. M. & Perry, R. D. Apr 1 2015 In : Environmental Microbiology. 17, 4, p. 947-959 13 p.

Research output: Research - peer-reviewArticle

Xenopsylla
Yersinia
Plague
Biofilms
Xenopsylla cheopis
2014
22 Citations

Bile acids and bicarbonate inversely regulate intracellular cyclic di-GMP in vibrio cholerae

Koestler, B. J. & Waters, C. M. 2014 In : Infection and Immunity. 82, 7, p. 3002-3014 13 p.

Research output: Research - peer-reviewArticle

Vibrio cholerae
Bicarbonates
Bile Acids and Salts
bis(3',5')-cyclic diguanylic acid
Enzymes

Cyclic di-GMP regulates the expression of virulence factors in Erwinia amylovora

Castiblanco, L. F., Edmunds, A. C., Waters, C. M. & Sundin, G. W. Oct 29 2014 Acta Horticulturae. International Society for Horticultural Science, Vol. 1056, p. 199-206 8 p. (Acta Horticulturae; vol. 1056)

Research output: ResearchChapter

Erwinia amylovora
virulence
biosynthesis
receptors
plant pathogenic bacteria
4 Citations

Deciphering the components that coordinately regulate virulence factors of the soft rot pathogen Dickeya dadantii

Wu, X., Zeng, Q., Koestler, B. J., Waters, C. M., Sundin, G. W., Hutchins, W. & Yang, C. H. Oct 1 2014 In : Molecular Plant-Microbe Interactions. 27, 10, p. 1119-1131 13 p.

Research output: Research - peer-reviewArticle

type III secretion system
virulence
pathogens
Dickeya dadantii
Glucans
34 Citations

Identification of small molecules inhibiting diguanylate cyclases to control bacterial biofilm development

Sambanthamoorthy, K., Luo, C., Pattabiraman, N., Feng, X., Koestler, B., Waters, C. M. & Palys, T. J. 2014 In : Biofouling. 30, 1, p. 17-28 12 p.

Research output: Research - peer-reviewArticle

Biofilms
diguanylate cyclase
biofilm
Infection
infection
3 Citations

Stimulation of innate immunity by in vivo cyclic di-GMP synthesis using adenovirus

Koestler, B. J., Seregin, S. S., Rastall, D. P. W., Aldhamen, Y. A., Godbehere, S., Amalfitano, A. & Waters, C. M. Nov 1 2014 In : Clinical and Vaccine Immunology. 21, 11, p. 1550-1559 10 p.

Research output: Research - peer-reviewArticle

Innate Immunity
Adenoviridae
bis(3',5')-cyclic diguanylic acid
diguanylate cyclase
Chemokines
17 Citations

The Vibrio cholerae diguanylate cyclase VCA0965 has an AGDEF active site and synthesizes cyclic di-GMP

Hunter, J. L., Severin, G. B., Koestler, B. J. & Waters, C. M. Feb 4 2014 In : BMC Microbiology. 14, 1, 22

Research output: Research - peer-reviewArticle

Vibrio cholerae
Catalytic Domain
diguanylate cyclase
bis(3',5')-cyclic diguanylic acid
Biofilms
2013
1 Citations

Bacterial wheel locks: Extracellular polysaccharide inhibits flagellar rotation

Waters, C. M. Feb 2013 In : Journal of Bacteriology. 195, 3, p. 409-410 2 p.

Research output: Research - peer-reviewArticle

Salmonella enteritidis
Bacterial Proteins
Cyclic GMP
Salmonella typhimurium
Cellulose
41 Citations

Cyclic di-GMP inhibits Vibrio cholerae motility by repressing induction of transcription and inducing extracellular polysaccharide production

Srivastava, D., Hsieh, M. L., Khataokar, A., Neiditch, M. B. & Waters, C. M. Dec 2013 In : Molecular Microbiology. 90, 6, p. 1262-1276 15 p.

Research output: Research - peer-reviewArticle

Vibrio cholerae
Polysaccharides
bis(3',5')-cyclic diguanylic acid
Cholera
Regulon
15 Citations

Cyclic Di-GMP Modulates the Disease Progression of Erwinia: Amylovora

Edmunds, A. C., Castiblanco, L. F., Sundin, G. W. & Waters, C. M. 2013 In : Journal of Bacteriology. 195, 20, p. 4778 1 p.

Research output: Research - peer-reviewArticle

Erwinia amylovora
Disease Progression
bis(3',5')-cyclic diguanylic acid
17 Citations

Cyclic Di-GMP modulates the disease progression of erwinia amylovora

Edmunds, A. C., Castiblanco, L. F., Sundin, G. W. & Waters, C. M. May 2013 In : Journal of Bacteriology. 195, 10, p. 2155-2165 11 p.

Research output: Research - peer-reviewArticle

Erwinia amylovora
Disease Progression
bis(3',5')-cyclic diguanylic acid
Biofilms
Infection
11 Citations
Vibrio cholerae
assays
enzymes
cholera
assay
18 Citations

Exposure of Salmonella enterica serovar typhimurium to a protective monoclonal iga triggers exopolysaccharide production via a diguanylate cyclase-dependent pathway

Amarasinghe, J. J., D'Hondt, R. E., Waters, C. M. & Mantis, N. J. Mar 2013 In : Infection and Immunity. 81, 3, p. 653-664 12 p.

Research output: Research - peer-reviewArticle

Salmonella enterica
Serogroup
diguanylate cyclase
Biofilms
O Antigens
38 Citations

Genetic analysis of agrobacterium tumefaciens unipolar polysaccharide production reveals complex integrated control of the motile-to-sessile switch

Xu, J., Kim, J., Koestler, B. J., Choi, J. H., Waters, C. M. & Fuqua, C. Sep 2013 In : Molecular Microbiology. 89, 5, p. 929-948 20 p.

Research output: Research - peer-reviewArticle

Agrobacterium tumefaciens
Polysaccharides
Mutation
Congo Red
Cellulose
12 Citations

Occurrence of cyclic di-GMP-modulating output domains in cyanobacteria: An illuminating perspective

Agostoni, M., Koestler, B. J., Waters, C. M., Williams, B. L. & Montgomery, B. L. Aug 13 2013 In : mBio. 4, 4

Research output: Research - peer-reviewArticle

Cyclic GMP
Cyanobacteria
bis(3',5')-cyclic diguanylic acid
Light
Second Messenger Systems
24 Citations

Post-transcriptional activation of a diguanylate cyclase by quorum sensing small RNAs promotes biofilm formation in Vibrio cholerae

Zhao, X., Koestler, B. J., Waters, C. M. & Hammer, B. K. Sep 2013 In : Molecular Microbiology. 89, 5, p. 989-1002 14 p.

Research output: Research - peer-reviewArticle

Quorum Sensing
Vibrio cholerae
Biofilms
Transcriptional Activation
RNA
80 Citations

STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection

Barker, J. R., Koestler, B. J., Carpenter, V. K., Burdette, D. L., Waters, C. M., Vance, R. E. & Valdivia, R. H. May 2013 In : mBio. 4, 3

Research output: Research - peer-reviewArticle

Interferon Type I
Chlamydia Infections
Chlamydia trachomatis
Cyclic AMP
Interferons
47 Citations

Two DHH subfamily 1 proteins in Streptococcus pneumoniae possess cyclic Di-AMP phosphodiesterase activity and affect bacterial growth and virulence

Bai, Y., Yang, J., Eisele, L. E., Underwood, A. J., Koestler, B. J., Waters, C. M., Metzger, D. W. & Bai, G. Nov 2013 In : Journal of Bacteriology. 195, 22, p. 5123-5132 10 p.

Research output: Research - peer-reviewArticle

Phosphoric Diester Hydrolases
Streptococcus pneumoniae
Cyclic AMP
Virulence
Growth
2012
50 Citations

A tangled web: Regulatory connections between quorum sensing and cyclic Di-GMP

Srivastava, D. & Waters, C. M. Sep 2012 In : Journal of Bacteriology. 194, 17, p. 4485-4493 9 p.

Research output: Research - peer-reviewArticle

Quorum Sensing
bis(3',5')-cyclic diguanylic acid
Bacteria
Population Density
Biofilms
33 Citations

Correlation between in vivo biofilm formation and virulence gene expression in Escherichia coli O104: H4

Safadi, R. A., Abu-Ali, G. S., Sloup, R. E., Rudrik, J. T., Waters, C. M., Eaton, K. A. & Manning, S. D. Jul 25 2012 In : PLoS One. 7, 7, e41628

Research output: Research - peer-reviewArticle

Biofilms
Virulence
Gene Expression
Escherichia coli O104
biofilm
59 Citations

Cyclic diguanylate inversely regulates motility and aggregation in clostridium difficile

Purcell, E. B., McKee, R. W., McBride, S. M., Waters, C. M. & Tamayo, R. Jul 2012 In : Journal of Bacteriology. 194, 13, p. 3307-3316 10 p.

Research output: Research - peer-reviewArticle

Clostridium difficile
bis(3',5')-cyclic diguanylic acid
Gram-Positive Bacteria
Second Messenger Systems
Biofilms

Evolution of resistance to quorum quenching in digital organisms

Beckmann, B. E., Knoester, D. B., Connelly, B. D., Waters, C. M. & Mckinley, P. K. Jul 2012 In : Artificial Life. 18, 3, p. 291-310 20 p.

Research output: Research - peer-reviewArticle

Quenching
Quorum Sensing
Bacteria
Anti-Bacterial Agents
Antibiotics
3 Citations

Evolution of resistance to quorum quenching in digital organisms.

Beckmann, B. E., Knoester, D. B., Connelly, B. D., Waters, C. M. & McKinley, P. K. Jun 2012 In : Artificial life. 18, 3, p. 291-310 20 p.

Research output: Research - peer-reviewArticle

Quenching
Quorum Sensing
Bacteria
Anti-Bacterial Agents
Antibiotics
31 Citations

Hfq-dependent, co-ordinate control of cyclic diguanylate synthesis and catabolism in the plague pathogen Yersinia pestis

Bellows, L. E., Koestler, B. J., Karaba, S. M., Waters, C. M. & Lathem, W. W. Nov 2012 In : Molecular Microbiology. 86, 3, p. 661-674 14 p.

Research output: Research - peer-reviewArticle

Yersinia pestis
Plague
bis(3',5')-cyclic diguanylic acid
Biofilms
RNA
60 Citations

Identification of small molecules that antagonize diguanylate cyclase enzymes to inhibit biofilm formation

Sambanthamoorthy, K., Sloup, R. E., Parashar, V., Smith, J. M., Kim, E. E., Semmelhack, M. F., Neiditch, M. B. & Waters, C. M. Oct 2012 In : Antimicrobial Agents and Chemotherapy. 56, 10, p. 5202-5211 10 p.

Research output: Research - peer-reviewArticle

Biofilms
Enzymes
diguanylate cyclase
Infection
bis(3',5')-cyclic diguanylic acid
62 Citations

Quantification of high-specificity cyclic diguanylate signaling

Massie, J. P., Reynolds, E. L., Koestler, B. J., Cong, J. P., Agostoni, M. & Waters, C. M. Jul 31 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 31, p. 12746-12751 6 p.

Research output: Research - peer-reviewArticle

bis(3',5')-cyclic diguanylic acid
Bacteria
Vibrio cholerae
Biofilms
Phosphoric Diester Hydrolases
1 Citations

The meteoric rise of the signaling molecule cyclic di-GMP

Waters, C. M. Aug 2012 In : Microbe. 7, 8, p. 353-359 7 p.

Research output: Research - peer-reviewArticle

bis(3',5')-cyclic diguanylic acid