Profile The profile is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 7 Similar Profiles
Liver Medicine & Life Sciences
Thromboplastin Medicine & Life Sciences
Wounds and Injuries Medicine & Life Sciences
Lipopolysaccharides Medicine & Life Sciences
1-Naphthylisothiocyanate Medicine & Life Sciences
Fibrin Medicine & Life Sciences
Inflammation Medicine & Life Sciences
Ranitidine Medicine & Life Sciences

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Grants 2010 2020

Publications 2002 2018

  • 30 h-Index
  • 91 Article
  • 1 Chapter
  • 1 Review article

Caspase inhibition reduces hepatic tissue factor-driven coagulation in vitro and in vivo

Kopec, A. K., Spada, A. P., Contreras, P. C., Mackman, N. & Luyendyk, J. P. Apr 1 2018 In : Toxicological Sciences. 162, 2, p. 396-405 10 p.

Research output: Contribution to journalArticle

Thromboplastin
Caspases
Coagulation
Liver
Hepatocytes

Plasminogen Activator Inhibitor-1 Reduces Tissue-Type Plasminogen Activator–Dependent Fibrinolysis and Intrahepatic Hemorrhage in Experimental Acetaminophen Overdose

Pant, A., Kopec, A. K., Baker, K. S., Cline-Fedewa, H., Lawrence, D. A. & Luyendyk, J. P. May 1 2018 In : American Journal of Pathology. 188, 5, p. 1204-1212 9 p.

Research output: Contribution to journalArticle

Plasminogen Activator Inhibitor 1
Fibrinolysis
Tissue Plasminogen Activator
Acetaminophen
Hemorrhage

A summary of the 6th international conference on coagulation in liver disease: Discussion, debate, deliberations

The Coagulation in Liver Disease 2015 Group Jan 1 2017 In : Annals of Hepatology. 16, 1, p. 12-15 4 p.

Research output: Contribution to journalArticle

7 Citations

Fibrin(ogen) drives repair after acetaminophen-induced liver injury via leukocyte αMβ2 integrin-dependent upregulation of Mmp12

Kopec, A. K., Joshi, N., Cline-Fedewa, H., Wojcicki, A. V., Ray, J. L., Sullivan, B. P., Froehlich, J. E., Johnson, B. F., Flick, M. J. & Luyendyk, J. P. Apr 1 2017 In : Journal of Hepatology. 66, 4, p. 787-797 11 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 12
Acetaminophen
Fibrin
Integrins
Leukocytes

Lymphocytes contribute to biliary injury and fibrosis in experimental xenobiotic-induced cholestasis

Joshi, N., Kopec, A. K., Cline-Fedewa, H. & Luyendyk, J. P. Feb 15 2017 In : Toxicology. 377, p. 73-80 8 p.

Research output: Contribution to journalArticle

1-Naphthylisothiocyanate
Lymphocytes
Cholestasis
Xenobiotics
Fibrosis