Publications 2001 2016

  • 15 h-Index
  • 18 Article
  • 1 Review article
2016

Function of Polycomb repressive complexes in stem cells

He, J. 2016 In : Frontiers in Biology. 11, 2, p. 65-74 10 p.

Research output: Contribution to journalReview article

stem cells
Stem Cells
stem
Developmental Genes
CpG Islands
2014
93 Citations

Tet3 and DNA replication mediate demethylation of both the maternal and paternal genomes in mouse zygotes

Shen, L., Inoue, A., He, J., Liu, Y., Lu, F. & Zhang, Y. 2014 In : Cell Stem Cell. 15, 4, p. 459-470 12 p.

Research output: Contribution to journalArticle

Zygote
DNA Replication
Mothers
Genome
DNA
2013
119 Citations

Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes

He, J., Shen, L., Wan, M., Taranova, O., Wu, H. & Zhang, Y. Apr 2013 In : Nature Cell Biology. 15, 4, p. 373-384 12 p.

Research output: Contribution to journalArticle

Polycomb Repressive Complex 1
Developmental Genes
CpG Islands
Embryonic Stem Cells
Polycomb-Group Proteins
2012
Induced Pluripotent Stem Cells
Transcriptional Activation
Cell Biology
89 Citations

Kdm2b promotes induced pluripotent stem cell generation by facilitating gene activation early in reprogramming

Liang, G., He, J. & Zhang, Y. May 2012 In : Nature Cell Biology. 14, 5, p. 457-466 10 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Transcriptional Activation
Epigenomics
Genetic Epigenesis
Histones
2011
117 Citations

Direct, Noncatalytic Mechanism of IKK Inhibition by A20

Skaug, B., Chen, J., Du, F., He, J., Ma, A. & Chen, Z. J. Nov 18 2011 In : Molecular Cell. 44, 4, p. 559-571 13 p.

Research output: Contribution to journalArticle

Polyubiquitin
Ubiquitination
Phosphotransferases
Zinc Fingers
B-Cell Lymphoma
109 Citations

DOT1L, the H3K79 methyltransferase, is required for MLL-AF9 - Mediated leukemogenesis

Nguyen, A. T., Taranova, O., He, J. & Zhang, Y. Jun 23 2011 In : Blood. 117, 25, p. 6912-6922 11 p.

Research output: Contribution to journalArticle

Methyltransferases
Leukemia
Genes
Methylation
Tamoxifen
30 Citations

Essential role of DOT1L in maintaining normal adult hematopoiesis

Nguyen, A. T., He, J., Taranova, O. & Zhang, Y. Sep 2011 In : Cell Research. 21, 9, p. 1370-1373 4 p.

Research output: Contribution to journalArticle

Estrogen Antagonists
Hematopoiesis
Methyltransferases
Tamoxifen
Bone Marrow Transplantation
88 Citations

KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia

He, J., Nguyen, A. T. & Zhang, Y. Apr 7 2011 In : Blood. 117, 14, p. 3869-3880 12 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Leukemia
Cell Aging
Maintenance
Histones
2010
4 Citations

Janus kinase 2: An epigenetic 'writer' that activates leukemogenic genes

He, J. & Zhang, Y. 2010 In : Journal of Molecular Cell Biology. 2, 5, p. 231-233 3 p.

Research output: Contribution to journalArticle

Janus Kinase 2
Epigenomics
Histones
Chromatin
Genes
2008
254 Citations

Generation of insulin-secreting islet-like clusters from human skin fibroblasts

Tateishi, K., He, J., Taranova, O., Liang, G., D'Alessio, A. C. & Zhang, Y. Nov 14 2008 In : Journal of Biological Chemistry. 283, 46, p. 31601-31607 7 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Fibroblasts
Stem cells
Skin
Insulin
112 Citations

Role of hPHF1 in H3K27 methylation and Hox gene silencing

Cao, R., Wang, H., He, J., Erdjument-Bromage, H., Tempst, P. & Zhang, Y. Mar 2008 In : Molecular and Cellular Biology. 28, 5, p. 1862-1872 11 p.

Research output: Contribution to journalArticle

Homeobox Genes
Gene Silencing
Methylation
Polycomb-Group Proteins
Histones
168 Citations

The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15Ink4b

He, J., Kallin, E. M., Tsukada, Y. I. & Zhang, Y. Nov 27 2008 In : Nature Structural and Molecular Biology. 15, 11, p. 1169-1175 7 p.

Research output: Contribution to journalArticle

Cell Aging
Cell Proliferation
Jumonji Domain-Containing Histone Demethylases
Carcinogenesis
Histone Demethylases
2006
33 Citations

An effective cancer vaccine modality: Lentiviral modification of dendritic cells expressing multiple cancer-specific antigens

Wang, B., He, J., Liu, C. & Chang, L. J. Apr 24 2006 In : Vaccine. 24, 17, p. 3477-3489 13 p.

Research output: Contribution to journalArticle

Cancer Vaccines
dendritic cells
Dendritic Cells
Neoplasm Antigens
vaccines
2005
47 Citations

Dynamic DNA methylation and histone modifications contribute to lentiviral transgene silencing in murine embryonic carcinoma cells

He, J., Yang, Q. & Chang, L. J. Nov 2005 In : Journal of Virology. 79, 21, p. 13497-13508 12 p.

Research output: Contribution to journalArticle

Histone Code
DNA methylation
DNA Methylation
Transgenes
histones
66 Citations

Lentiviral siRNAs targeting multiple highly conserved RNA sequences of human immunodeficiency virus type 1

Chang, L. J., Liu, X. & He, J. Jul 2005 In : Gene Therapy. 12, 14, p. 1133-1144 12 p.

Research output: Contribution to journalArticle

Conserved Sequence
HIV-1
Small Interfering RNA
Viral RNA
HIV
2004
30 Citations

Alteration of T cell immunity by lentiviral transduction of human monocyte-derived dendritic cells

Chen, X., He, J. & Chang, L. J. Nov 1 2004 In : Retrovirology. 1

Research output: Contribution to journalArticle

Dendritic Cells
Monocytes
Immunity
T-Lymphocytes
HIV-1
12 Citations

Functional characterization of hepatoma-specific stem cell antigen-2

He, J. & Chang, L. J. Jun 2004 In : Molecular Carcinogenesis. 40, 2, p. 90-103 14 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Apoptosis
Tumor Necrosis Factor Receptors
Neoplasm Antigens
RNA Interference
2001
18 Citations

Retroviral vectors for gene therapy of AIDS and cancer

Chang, L. J. & He, J. 2001 In : Current Opinion in Molecular Therapeutics. 3, 5, p. 468-475 8 p.

Research output: Contribution to journalArticle

Genetic Therapy
Acquired Immunodeficiency Syndrome
Neoplasms
Hematopoietic Stem Cells
HIV Infections