Publications 2011 2017

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  • 15 Article
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2017

Anions for Near-Infrared Selective Organic Salt Photovoltaics

Traverse, C. J., Young, M., Suddard-Bangsund, J., Patrick, T., Bates, M., Chen, P., Wingate, B., Lunt, S. Y., Anctil, A. & Lunt, R. R. Dec 1 2017 In : Scientific Reports. 7, 1, 16399

Research output: Research - peer-reviewArticle

Anions
Salts
Infrared radiation
Functional groups
Borates
1 Citations

Deciphering metabolic rewiring in breast cancer subtypes

Ogrodzinski, M. P., Bernard, J. J. & Lunt, S. Y. 2017 (Accepted/In press) In : Translational Research.

Research output: Research - peer-reviewArticle

Metabolism
Cells
Breast Neoplasms
Therapeutics
Metabolic Diseases

Fibroblast growth factor receptor is a mechanistic link between visceral adiposity and cancer

Chakraborty, D., Benham, V., Bullard, B., Kearney, T., Hsia, H. C., Gibbon, D., Demireva, E. Y., Lunt, S. Y. & Bernard, J. J. Nov 30 2017 In : Oncogene. 36, 48, p. 6668-6679 12 p.

Research output: Research - peer-reviewArticle

Fibroblast Growth Factor Receptors
Intra-Abdominal Fat
Adiposity
Neoplasms
Fibroblast Growth Factor 2
1 Citations

Prediction of years of life after diagnosis of breast cancer using omics and omic-by-treatment interactions

González-Reymúndez, A., de los Campos, G., Gutiérrez, L., Lunt, S. Y. & Vazquez, A. I. Mar 8 2017 (Accepted/In press) In : European Journal of Human Genetics.

Research output: Research - peer-reviewArticle

Breast Neoplasms
Therapeutics
Neoplasms
Survival
Gene Dosage
2016
4 Citations

Organic Heptamethine Salts for Photovoltaics and Detectors with Near-Infrared Photoresponse up to 1600 nm

Young, M., Suddard-Bangsund, J., Patrick, T. J., Pajares, N., Traverse, C. J., Barr, M. C., Lunt, S. Y. & Lunt, R. R. 2016 (Accepted/In press) In : Advanced Optical Materials.

Research output: Research - peer-reviewArticle

Salts
Infrared radiation
Detectors
salts
detectors
12 Citations

Pyruvate kinase isoform switching and hepatic metabolic reprogramming by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin

Nault, R., Fader, K. A., Kirby, M. P., Ahmed, S., Matthews, J., Jones, A. D., Lunt, S. Y. & Zacharewski, T. R. Feb 1 2016 In : Toxicological Sciences. 149, 2, p. 358-371 14 p., kfv245

Research output: Research - peer-reviewArticle

Pyruvate Kinase
Protein Isoforms
Impurities
1,4-dioxin
Liver
2015
109 Citations

A roadmap for interpreting 13C metabolite labeling patterns from cells

Buescher, J. M. , Antoniewicz, M. R. , Boros, L. G. , Burgess, S. C. , Brunengraber, H. , Clish, C. B. , DeBerardinis, R. J. , Feron, O. , Frezza, C. , Ghesquiere, B. , Gottlieb, E. , Hiller, K. , Jones, R. G. , Kamphorst, J. J. , Kibbey, R. G. , Kimmelman, A. C. , Locasale, J. W. , Lunt, S. Y. , Maddocks, O. D. K. , Malloy, C. & 17 others Metallo, C. M., Meuillet, E. J., Munger, J., Nöh, K., Rabinowitz, J. D., Ralser, M., Sauer, U., Stephanopoulos, G., St-Pierre, J., Tennant, D. A., Wittmann, C., Vander Heiden, M. G., Vazquez, A., Vousden, K., Young, J. D., Zamboni, N. & Fendt, S. M. Aug 1 2015 In : Current Opinion in Biotechnology. 34, p. 189-201 13 p.

Research output: Research - peer-reviewArticle

Data integration
Metabolites
Metabolism
Labeling
Nutrients
4 Citations

Erratum: Fatty acid carbon is essential for dNTP synthesis in endothelial cells (Nature (2015) 520 (192-197) DOI:10.1038/nature14362)

Schoors, S. , Bruning, U. , Missiaen, R. , Queiroz, K. C. S. , Borgers, G. , Elia, I. , Zecchin, A. , Cantelmo, A. R. , Christen, S. , Goveia, J. , Heggermont, W. , Goddë, L. , Vinckier, S. , Van Veldhoven, P. P. , Eelen, G. , Schoonjans, L. , Gerhardt, H. , Dewerchin, M. , Baes, M. , De Bock, K. & 4 others Ghesquière, B., Lunt, S. Y., Fendt, S. M. & Carmeliet, P. Oct 1 2015 In : Nature. 526, 7571, p. 144 1 p.

Research output: Research - peer-reviewArticle

99 Citations

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

Schoors, S. , Bruning, U. , Missiaen, R. , Queiroz, K. C. S. , Borgers, G. , Elia, I. , Zecchin, A. , Cantelmo, A. R. , Christen, S. , Goveia, J. , Heggermont, W. , Goddé, L. , Vinckier, S. , Van Veldhoven, P. P. , Eelen, G. , Schoonjans, L. , Gerhardt, H. , Dewerchin, M. , Baes, M. , De Bock, K. & 4 others Ghesquière, B., Lunt, S. Y., Fendt, S. M. & Carmeliet, P. Apr 9 2015 In : Nature. 520, 7546, p. 192-197 6 p.

Research output: Research - peer-reviewArticle

Fatty Acids
Carbon
Endothelial Cells
Acetyl Coenzyme A
Aspartic Acid
61 Citations

Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation

Lunt, S. Y. , Muralidhar, V. , Hosios, A. M. , Israelsen, W. J. , Gui, D. Y. , Newhouse, L. , Ogrodzinski, M. , Hecht, V. , Xu, K. , Acevedo, P. N. M. , Hollern, D. P. , Bellinger, G. , Dayton, T. L. , Christen, S. , Elia, I. , Dinh, A. T. , Stephanopoulos, G. , Manalis, S. R. , Yaffe, M. B. , Andrechek, E. R. & 2 others Fendt, S. M. & Vander Heiden, M. G. Jan 8 2015 In : Molecular Cell. 57, 1, p. 95-107 13 p.

Research output: Research - peer-reviewArticle

Pyruvate Kinase
Protein Isoforms
Nucleotides
Cell Proliferation
DNA
2013
18 Citations

Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation

Martin, E. S. , Belmont, P. J. , Sinnamon, M. J. , Richard, L. G. , Yuan, J. , Coffee, E. M. , Roper, J. , Lee, L. , Heidari, P. , Lunt, S. Y. , Goel, G. , Ji, X. , Xie, Z. , Xie, T. , Lamb, J. , Weinrich, S. L. , VanArsdale, T. , Bronson, R. T. , Xavier, R. J. , Vander Heiden, M. G. & 3 others Kan, J. L. C., Mahmood, U. & Hung, K. E. Jun 1 2013 In : Clinical Cancer Research. 19, 11, p. 2929-2940 12 p.

Research output: Research - peer-reviewArticle

Drug Discovery
Colonic Neoplasms
Colorectal Neoplasms
Transplants
Cell Line
2012
3 Citations

Erratum: Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis (Nature Chemical Biology (2012) 8 (839-847))

Anastasiou, D. , Yu, Y. , Israelsen, W. J. , Jiang, J. K. , Boxer, M. B. , Hong, B. S. , Tempel, W. , Dimov, S. , Shen, M. , Jha, A. , Yang, H. , Mattaini, K. R. , Metallo, C. M. , Fiske, B. P. , Courtney, K. D. , Malstrom, S. , Khan, T. M. , Kung, C. , Skoumbourdis, A. P. , Veith, H. & 23 others Southall, N., Walsh, M. J., Brimacombe, K. R., Leister, W., Lunt, S. Y., Johnson, Z. R., Yen, K. E., Kunii, K., Davidson, S. M., Christofk, H. R., Austin, C. P., Inglese, J., Harris, M. H., Asara, J. M., Stephanopoulos, G., Salituro, F. G., Jin, S., Dang, L., Auld, D. S., Park, H. W., Cantley, L. C., Thomas, C. J. & Vander Heiden, M. G. Dec 2012 In : Nature Chemical Biology. 8, 12, p. 1008 1 p.

Research output: Research - peer-reviewArticle

233 Citations

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Anastasiou, D. , Yu, Y. , Israelsen, W. J. , Jiang, J. K. , Boxer, M. B. , Hong, B. S. , Tempel, W. , Dimov, S. , Shen, M. , Jha, A. , Yang, H. , Mattaini, K. R. , Metallo, C. M. , Fiske, B. P. , Courtney, K. D. , Malstrom, S. , Khan, T. M. , Kung, C. , Skoumbourdis, A. P. , Veith, H. & 23 others Southall, N., Walsh, M. J., Brimacombe, K. R., Leister, W., Lunt, S. Y., Johnson, Z. R., Yen, K. E., Kunii, K., Davidson, S. M., Christofk, H. R., Austin, C. P., Inglese, J., Harris, M. H., Asara, J. M., Stephanopoulos, G., Salituro, F. G., Jin, S., Dang, L., Auld, D. S., Park, H. W., Cantley, L. C., Thomas, C. J. & Vander Heiden, M. G. 2012 In : Nature Chemical Biology. 8, 10, p. 839-847 9 p.

Research output: Research - peer-reviewArticle

Pyruvate Kinase
Carcinogenesis
Neoplasms
Cell Proliferation
Enzymes
2011
674 Citations

Aerobic glycolysis: Meeting the metabolic requirements of cell proliferation

Lunt, S. Y. & Vander Heiden, M. G. 2011 In : Annual Review of Cell and Developmental Biology. 27, p. 441-464 24 p.

Research output: Research - peer-reviewArticle

Glycolysis
Cell Proliferation
Neoplasms
Biomass
Respiration
117 Citations

Metabolic pathway alterations that support: Cell Proliferation

Heiden Vander, M. G., Lunt, S. Y., Dayton, T. L., Fiske, B. P., Israelsen, W. J., Mattaini, K. R., Vokes, N. I., Stephanopoulos, G., Cantley, L. C., Metallo, C. M. & Locasale, J. W. 2011 In : Cold Spring Harbor Symposia on Quantitative Biology. 76, p. 325-334 10 p.

Research output: Research - peer-reviewArticle

Cell proliferation
Metabolism
Metabolic Networks and Pathways
Cell Proliferation
Phosphoenolpyruvate