Publications 1995 2017

  • 13 h-Index
  • 36 Article
  • 8 Conference contribution
  • 1 Chapter
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2017

Use of Brevibacillus choshinensis for the production of biologically active brain-derived neurotrophic factor (BDNF)

Angart, P. A., Carlson, R. J., Thorwall, S. & Patrick Walton, S. May 2 2017 (Accepted/In press) In : Applied Microbiology and Biotechnology. p. 1-8 8 p.

Research output: Research - peer-reviewArticle

Brevibacillus
Brain-Derived Neurotrophic Factor
Proteins
Cystine
Nerve Growth Factors

Work in progress: A study of augmented reality for the development of spatial reasoning ability

Bell, J. E., Hinds, T. J., Walton, S. P., Cugini, C., Cheng, C., Freer, D. J., Cain, W. & Klautke, H. Jun 24 2017 In : ASEE Annual Conference and Exposition, Conference Proceedings. 2017-June

Research output: Research - peer-reviewArticle

2016

Characterization of transcription factor response kinetics in parallel

Bilgin, B., Nath, A., Chan, C. & Walton, S. P. 2016 In : BMC Biotechnology. 16, 1, 62

Research output: Research - peer-reviewArticle

Transcription Factors
Palmitic Acid
Tumor Necrosis Factor-alpha
Glucocorticoid Receptors
TATA-Box Binding Protein
1 Citations

Terminal Duplex Stability and Nucleotide Identity Differentially Control siRNA Loading and Activity in RNA Interference

Angart, P. A., Carlson, R. J., Adu-Berchie, K. & Walton, S. P. Oct 1 2016 In : Nucleic Acid Therapeutics. 26, 5, p. 309-317 9 p.

Research output: Research - peer-reviewArticle

RNA Interference
Small Interfering RNA
Nucleotides
RNA
RNA-Induced Silencing Complex
2015
3 Citations

Brain derived neurotrophic factor release from layer-by-layer coated agarose nerve guidance scaffolds

Lynam, D. A., Shahriari, D., Wolf, K. J., Angart, P. A., Koffler, J., Tuszynski, M. H., Chan, C., Walton, P. & Sakamoto, J. May 1 2015 In : Acta Biomaterialia. 18, p. 128-131 4 p.

Research output: Research - peer-reviewArticle

Scaffolds
Brain
Nerve Growth Factors
Brain-Derived Neurotrophic Factor
Sepharose
1 Citations

How can novel microscopic approaches shed light on the function of nucleic acid-based drugs?

Vocelle, D., Chan, C. & Walton, S. P. Sep 1 2015 In : Future Medicinal Chemistry. 7, 13, p. 1623-1625 3 p.

Research output: Research - peer-reviewArticle

2014
4 Citations

Improved asymmetry prediction for short interfering RNAs

Malefyt, A. P., Wu, M., Vocelle, D. B., Kappes, S. J., Lindeman, S. D., Chan, C. & Walton, S. P. Jan 2014 In : FEBS Journal. 281, 1, p. 320-330 11 p.

Research output: Research - peer-reviewArticle

Small Interfering RNA
Thermodynamics
Thermodynamic stability
Nucleotides
Protein Kinases
2013
13 Citations

Design of siRNA therapeutics from the molecular scale

Angart, P., Vocelle, D., Chan, C. & Patrick Walton, S. Mar 25 2013 In : Pharmaceuticals. 6, 4, p. 440-468 29 p.

Research output: Research - peer-reviewArticle

Small Interfering RNA
Therapeutics
Biological Phenomena
Drug Industry
RNA Interference
7 Citations

Quantitative, solution-phase profiling of multiple transcription factors in parallel

Bilgin, B., Liu, L., Chan, C. & Patrick Walton, S. Mar 2013 In : Analytical and Bioanalytical Chemistry. 405, 8, p. 2461-2468 8 p.

Research output: Research - peer-reviewArticle

Transcription Factors
Assays
Genes
Amplification
DNA
2012

Chemical engineering (and materials science and engineering)

Patrick Walton, S., Ofoli, R. Y., Depriest, J. L. & Seeley, L. A. Jun 2012 In : Chemical Engineering Education. 46, 3, p. 146-151 6 p.

Research output: Research - peer-reviewArticle

Chemical engineering
Materials science
Education
10 Citations

Latest developments in experimental and computational approaches to characterize protein-lipid interactions

Cho, H., Wu, M., Bilgin, B., Walton, S. P. & Chan, C. Nov 2012 In : Proteomics. 12, 22, p. 3273-3285 13 p.

Research output: Research - peer-reviewArticle

Lipids
Proteins
Technology
Molecules
DNA
1 Citations

Text messaging as a tool for engaging chemical engineering students

Walton, S. P., Briedis, D., Lindeman, S. D., Malefyt, A. P. & Sticklen, J. Mar 2012 In : Chemical Engineering Education. 46, 2, p. 80-86 7 p.

Research output: Research - peer-reviewArticle

2011
3 Citations

Molecular mechanism by which palmitate inhibits PKR autophosphorylation

Cho, H., Mukherjee, S., Palasuberniam, P., Pillow, L., Bilgin, B., Nezich, C., Walton, S. P., Feig, M. & Chan, C. Feb 15 2011 In : Biochemistry. 50, 6, p. 1110-1119 10 p.

Research output: Research - peer-reviewArticle

Palmitates
Phosphotransferases
Adenosine Triphosphate
Binding Sites
Proteins

Special session: What works to retain students in chemical engineering programs

Minerick, A. R., Visco, D. P., Montgomery, S. M., Briedis, D., Buch, N., Sticklen, J., McDonough, C. A., Walton, S. P., Portis, A. M., Chimowitz, E. H., Rochefort, W. E., Levien, K. L., Elbashir, N., Condit, J. & Lindeman, S. 2011 In : ASEE Annual Conference and Exposition, Conference Proceedings.

Research output: Research - peer-reviewArticle

3 Citations

Synergy analysis reveals association between insulin signaling and desmoplakin expression in palmitate treated HepG2 cells

Wang, X., Nath, A., Yang, X., Portis, A., Walton, S. P. & Chan, C. Nov 23 2011 In : PLoS One. 6, 11, e28138

Research output: Research - peer-reviewArticle

palmitates
insulin
cells
Desmoplakins
Palmitates
2010
14 Citations

Confocal microscopy for the analysis of siRNA delivery by polymeric nanoparticles

Portis, A. M., Carballo, G., Baker, G. L., Chan, C. & Walton, S. P. Sep 2010 In : Microscopy Research and Technique. 73, 9, p. 878-885 8 p.

Research output: Research - peer-reviewArticle

Confocal Microscopy
Nanoparticles
Small Interfering RNA
delivery
microscopy
46 Citations

Designing highly active siRNAs for therapeutic applications

Patrick Walton, S., Wu, M., Gredell, J. A. & Chan, C. Dec 2010 In : FEBS Journal. 277, 23, p. 4806-4813 8 p.

Research output: Research - peer-reviewArticle

Small Interfering RNA
Therapeutics
RNA Interference
RNA
Thermodynamics
17 Citations

Development of a dual-aptamer-based multiplex protein biosensor

Xie, S. & Walton, S. P. Aug 2010 In : Biosensors and Bioelectronics. 25, 12, p. 2663-2668 6 p.

Research output: Research - peer-reviewArticle

Biosensing Techniques
Proteins
Biosensors
Biological Phenomena
Thrombin
1 Citations

Engineering active siRNA therapeutics

Patrick Walton, S. Dec 2010 In : FEBS Journal. 277, 23, p. 4805 1 p.

Research output: Research - peer-reviewArticle

32 Citations

Recognition of siRNA asymmetry by TAR RNA binding protein

Gredell, J. A., Dittmer, M. J., Wu, M., Chan, C. & Walton, S. P. Apr 13 2010 In : Biochemistry. 49, 14, p. 3148-3155 8 p.

Research output: Research - peer-reviewArticle

Small Interfering RNA
trans-activation responsive RNA-binding protein
RNA-Induced Silencing Complex
RNA Interference
Proteins
2009
6 Citations

Application and analysis of structure-switching aptamers for small molecule quantification

Xie, S. & Walton, S. P. Apr 13 2009 In : Analytica Chimica Acta. 638, 2, p. 213-219 7 p.

Research output: Research - peer-reviewArticle

Biosensors
Molecules
nucleic acid
analysis
Biosensing Techniques
9 Citations

Effect of siRNA terminal mismatches on TRBP and Dicer binding and silencing efficacy

Kini, H. K. & Walton, S. P. Nov 2009 In : FEBS Journal. 276, 22, p. 6576-6585 10 p.

Research output: Research - peer-reviewArticle

Small Interfering RNA
RNA-Binding Proteins
Nucleotides
RNA-Induced Silencing Complex
Human Immunodeficiency Virus Proteins
8 Citations

Emerging affinity-based techniques in proteomics

Xie, S., Moya, C., Bilgin, B., Jayaraman, A. & Walton, S. P. Oct 2009 In : Expert Review of Proteomics. 6, 5, p. 573-583 11 p.

Research output: Research - peer-reviewArticle

Proteome
Proteins
Proteomics
4 Citations

Proteomics: Technology development and applications

Walton, S. P. & Jayaraman, A. Feb 2009 In : Expert Review of Proteomics. 6, 1, p. 23-25 3 p.

Research output: Research - peer-reviewArticle

Proteomics
Industrial Development
Engineers
Electrophoresis
Chemical Engineering
2008
36 Citations

Impact of target mRNA structure on siRNA silencing efficiency: A large-scale study

Gredell, J. A., Berger, A. K. & Walton, S. P. Jul 1 2008 In : Biotechnology and Bioengineering. 100, 4, p. 744-755 12 p.

Research output: Research - peer-reviewArticle

Small Interfering RNA
Messenger RNA
Gene Silencing
Genes
Hep G2 Cells
2007
15 Citations

In vitro binding of single-stranded RNA by human Dicer

Kini, H. K. & Walton, S. P. Dec 11 2007 In : FEBS Letters. 581, 29, p. 5611-5616 6 p.

Research output: Research - peer-reviewArticle

RNA
In Vitro Techniques
Hydroxyl Radical
Double-Stranded RNA
Divalent Cations
2006
7 Citations

Analysis of hybridization on the molecular barcode GeneChip microarray

Walton, S. P., Mindrinos, M. N. & Davis, R. W. Sep 22 2006 In : Biochemical and Biophysical Research Communications. 348, 2, p. 689-696 8 p.

Research output: Research - peer-reviewArticle

Microarray Analysis
Systems Analysis
Polymerase Chain Reaction
Microarrays
Mirrors
1 Citations

Biological network analyses: Computational genomics and systems approaches

Walton, S. P., Li, Z. & Chan, C. Jan 1 2006 In : Molecular Simulation. 32, 3-4, p. 203-209 7 p.

Research output: Research - peer-reviewArticle

Biological Networks
Genomics
Throughput
Chemical engineering
Engineers
2002
46 Citations

Thermodynamic and kinetic characterization of antisense oligodeoxynucleotide binding to a structured mRNA

Patrick Walton, S., Stephanopoulos, G. N., Yarmush, M. L. & Roth, C. M. 2002 In : Biophysical Journal. 82, 1, p. 366-377 12 p.

Research output: Research - peer-reviewArticle

Oligodeoxyribonucleotides
Thermodynamics
Messenger RNA
RNA
beta-Globins
2001
10 Citations

Coupling of inflammatory cytokine signaling pathways probed by measurements of extracellular acidification rate

Roth, C. M., Kohen, R. L., Walton, S. P. & Yarmush, M. L. Jan 31 2001 In : Biophysical Chemistry. 89, 1, p. 1-12 12 p.

Research output: Research - peer-reviewArticle

Interleukin-1
Cytokines
Acidification
cells
Hep G2 Cells
25 Citations

Rational selection and quantitative evaluation of antisense oligonucleotides

Jayaraman, A., Walton, S. P., Yarmush, M. L. & Roth, C. M. Aug 30 2001 In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1520, 2, p. 105-114 10 p.

Research output: Research - peer-reviewArticle

Antisense Oligonucleotides
Oligonucleotides
Messenger RNA
Gene Expression
Gene expression
1999
39 Citations

Prediction of antisense oligonucleotide binding affinity to a structured RNA target

Walton, S. P., Stephanopoulos, G. N., Yarmush, M. L. & Roth, C. M. Oct 5 1999 In : Biotechnology and Bioengineering. 65, 1, p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Antisense Oligonucleotides
RNA
Messenger RNA
Oligonucleotides
beta-Globins
1998
17 Citations

Visualization of the hinge flow in a 5: 1 scaled model of the medtronic parallel bileaflet heart valve prosthesis

Healy, T. M., Fontaine, A. A., Ellis, J. T., Walton, S. P. & Yoganathan, A. P. 1998 In : Experiments in Fluids. 25, 5-6, p. 512-518 7 p.

Research output: Research - peer-reviewArticle

Heart valve prostheses
Hinges
Visualization
heart valves
hinges
1996
15 Citations

Comparison of magnetic resonance imaging and laser doppler anemometry velocity measurements downstream of replacement heart valves: Implications for in vivo assessment of prosthetic valve function

Fontaine, A. A., Heinrich, R. S., Walker, P. G., Pedersen, E. M., Scheidegger, M. B., Boesiger, P., Walton, S. P. & Yoganathan, A. P. Jan 1996 In : Journal of Heart Valve Disease. 5, 1, p. 66-73 8 p.

Research output: Research - peer-reviewArticle

Heart Valves
Lasers
Magnetic Resonance Imaging
Culture Diffusion Chambers
Hemodynamics
1995
27 Citations

Magnetic resonance velocity imaging: A new method for prosthetic heart valve study

Walker, P. G., Pedersen, E. M., Oyre, S., Flepp, L., Ringgaard, S., Heinrich, R. S., Walton, S. P., Hasenkam, J. M., Jorgensen, H. S. & Yoganathan, A. P. 1995 In : Journal of Heart Valve Disease. 4, 3, p. 296-307 12 p.

Research output: Research - peer-reviewArticle

Heart Valves
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
Magnetic Fields
In Vitro Techniques