Profile The profile is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

B-Lymphocytes Medicine & Life Sciences
In Vitro Techniques Medicine & Life Sciences
Gene Regulatory Networks Medicine & Life Sciences
Cell Differentiation Medicine & Life Sciences
Tetrachlorodibenzodioxin Medicine & Life Sciences
Liver Medicine & Life Sciences
Homeostasis Medicine & Life Sciences
Cyclic AMP Receptor Protein Chemical Compounds

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Grants 2013 2018

Publications 2005 2015

8 Citations

Adaptive posttranslational control in cellular stress response pathways and its relationship to toxicity testing and safety assessment

Zhang, Q., Bhattacharya, S., Pi, J., Clewell, R. A., Carmichael, P. L. & Andersen, M. E. Oct 1 2015 In : Toxicological Sciences. 147, 2, p. 302-316 15 p., kfv130

Research output: Contribution to journalArticle

Safety
Genes
Addison Disease
Blood Flow Velocity
Heat-Shock Proteins
29 Citations

Molecular signaling network motifs provide a mechanistic basis for cellular threshold responses

Zhang, Q., Bhattacharya, S., Conolly, R. B., Clewell, H. J., Kaminski, N. E. & Andersen, M. E. 2015 In : Environmental Health Perspectives. 122, 12, p. 1261-1270 10 p.

Research output: Contribution to journalArticle

In Vitro Techniques
Biological Models
Homeostasis
Apoptosis
Health
35 Citations

A map of the PPARα transcription regulatory network for primary human hepatocytes

McMullen, P. D., Bhattacharya, S., Woods, C. G., Sun, B., Yarborough, K., Ross, S. M., Miller, M. E., McBride, M. T., Lecluyse, E. L., Clewell, R. A. & Andersen, M. E. Feb 25 2014 In : Chemico-Biological Interactions. 209, 1, p. 14-24 11 p.

Research output: Contribution to journalArticle

Hepatocytes
Transcription Factors
Gene Expression
Genes
Cyclic AMP Receptor Protein
8 Citations

All-or-none suppression of B cell terminal differentiation by environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin

Zhang, Q., Kline, D. E., Bhattacharya, S., Crawford, R. B., Conolly, R. B., Thomas, R. S., Andersen, M. E. & Kaminski, N. E. Apr 1 2013 In : Toxicology and Applied Pharmacology. 268, 1, p. 17-26 10 p.

Research output: Contribution to journalArticle

Tetrachlorodibenzodioxin
Cell Differentiation
B-Lymphocytes
Castration
Aryl Hydrocarbon Receptors
341 Citations

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

Godoy, P. , Hewitt, N. J. , Albrecht, U. , Andersen, M. E. , Ansari, N. , Bhattacharya, S. , Bode, J. G. , Bolleyn, J. , Borner, C. , Böttger, J. , Braeuning, A. , Budinsky, R. A. , Burkhardt, B. , Cameron, N. R. , Camussi, G. , Cho, C. S. , Choi, Y. J. , Craig Rowlands, J. , Dahmen, U. , Damm, G. & 73 others Dirsch, O., Donato, M. T., Dong, J., Dooley, S., Drasdo, D., Eakins, R., Ferreira, K. S., Fonsato, V., Fraczek, J., Gebhardt, R., Gibson, A., Glanemann, M., Goldring, C. E. P., Gómez-Lechón, M. J., Groothuis, G. M. M., Gustavsson, L., Guyot, C., Hallifax, D., Hammad, S., Hayward, A., Häussinger, D., Hellerbrand, C., Hewitt, P., Hoehme, S., Holzhütter, H. G., Houston, J. B., Hrach, J., Ito, K., Jaeschke, H., Keitel, V., Kelm, J. M., Kevin Park, B., Kordes, C., Kullak-Ublick, G. A., Lecluyse, E. L., Lu, P., Luebke-Wheeler, J., Lutz, A., Maltman, D. J., Matz-Soja, M., McMullen, P., Merfort, I., Messner, S., Meyer, C., Mwinyi, J., Naisbitt, D. J., Nussler, A. K., Olinga, P., Pampaloni, F., Pi, J., Pluta, L., Przyborski, S. A., Ramachandran, A., Rogiers, V., Rowe, C., Schelcher, C., Schmich, K., Schwarz, M., Singh, B., Stelzer, E. H. K., Stieger, B., Stöber, R., Sugiyama, Y., Tetta, C., Thasler, W. E., Vanhaecke, T., Vinken, M., Weiss, T. S., Widera, A., Woods, C. G., Xu, J. J., Yarborough, K. M. & Hengstler, J. G. Aug 2013 In : Archives of Toxicology. 87, 8, p. 1315-1530 216 p.

Research output: Contribution to journalArticle

Hepatocytes
Liver
In Vitro Techniques
Fibrin
Metabolism