Publications 2005 2017

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2017
1 Citations

Aryl hydrocarbon receptor activation suppresses EBF1 and PAX5 and impairs human B Lymphopoiesis

Li, J., Bhattacharya, S., Zhou, J., Phadnis-Moghe, A. S., Crawford, R. B. & Kaminski, N. E. Nov 15 2017 In : Journal of Immunology. 199, 10, p. 3504-3515 12 p.

Research output: Contribution to journalArticle

Lymphopoiesis
Aryl Hydrocarbon Receptors
B-Lymphocytes
Hematopoietic Stem Cells
Cell Lineage

A Theoretical Model of the Wnt Signaling Pathway in the Epithelial Mesenchymal Transition

Gasior, K., Hauck, M., Wilson, A. & Bhattacharya, S. Oct 10 2017 In : Theoretical Biology and Medical Modelling. 14, 1, 19

Research output: Contribution to journalArticle

Wnt Signaling Pathway
Gastropoda
Epithelial-Mesenchymal Transition
Signaling Pathways
Cadherins
1 Citations

Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells

Jagannathan, L., Jose, C. C., Tanwar, V. S., Bhattacharya, S. & Cuddapah, S. Jan 1 2017 In : Toxicology Research. 6, 3, p. 312-323 12 p.

Research output: Contribution to journalArticle

Mercury
Transcriptome
Biological Phenomena
Polychlorinated Dibenzodioxins
Toxicology
2015
8 Citations

Adaptive posttranslational control in cellular stress response pathways and its relationship to toxicity testing and safety assessment

Zhang, Q., Bhattacharya, S., Pi, J., Clewell, R. A., Carmichael, P. L. & Andersen, M. E. Oct 1 2015 In : Toxicological Sciences. 147, 2, p. 302-316 15 p., kfv130

Research output: Contribution to journalArticle

Toxicity
Safety
Testing
Heat-Shock Proteins
Genes
32 Citations

Molecular signaling network motifs provide a mechanistic basis for cellular threshold responses

Zhang, Q., Bhattacharya, S., Conolly, R. B., Clewell, H. J., Kaminski, N. E. & Andersen, M. E. 2015 In : Environmental Health Perspectives. 122, 12, p. 1261-1270 10 p.

Research output: Contribution to journalArticle

Biological Models
Homeostasis
Apoptosis
In Vitro Techniques
Health
2014
40 Citations

A map of the PPARα transcription regulatory network for primary human hepatocytes

McMullen, P. D., Bhattacharya, S., Woods, C. G., Sun, B., Yarborough, K., Ross, S. M., Miller, M. E., McBride, M. T., Lecluyse, E. L., Clewell, R. A. & Andersen, M. E. Feb 25 2014 In : Chemico-Biological Interactions. 209, 1, p. 14-24 11 p.

Research output: Contribution to journalArticle

Transcription
Peroxisome Proliferators
Hepatocytes
Transcription Factors
Genes
2013
11 Citations

All-or-none suppression of B cell terminal differentiation by environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin

Zhang, Q., Kline, D. E., Bhattacharya, S., Crawford, R. B., Conolly, R. B., Thomas, R. S., Andersen, M. E. & Kaminski, N. E. Apr 1 2013 In : Toxicology and Applied Pharmacology. 268, 1, p. 17-26 10 p.

Research output: Contribution to journalArticle

Cell Differentiation
B-Lymphocytes
Cells
Impurities
Aryl Hydrocarbon Receptors
412 Citations

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

Godoy, P. , Hewitt, N. J. , Albrecht, U. , Andersen, M. E. , Ansari, N. , Bhattacharya, S. , Bode, J. G. , Bolleyn, J. , Borner, C. , Böttger, J. , Braeuning, A. , Budinsky, R. A. , Burkhardt, B. , Cameron, N. R. , Camussi, G. , Cho, C. S. , Choi, Y. J. , Craig Rowlands, J. , Dahmen, U. , Damm, G. & 73 others Dirsch, O., Donato, M. T., Dong, J., Dooley, S., Drasdo, D., Eakins, R., Ferreira, K. S., Fonsato, V., Fraczek, J., Gebhardt, R., Gibson, A., Glanemann, M., Goldring, C. E. P., Gómez-Lechón, M. J., Groothuis, G. M. M., Gustavsson, L., Guyot, C., Hallifax, D., Hammad, S., Hayward, A., Häussinger, D., Hellerbrand, C., Hewitt, P., Hoehme, S., Holzhütter, H. G., Houston, J. B., Hrach, J., Ito, K., Jaeschke, H., Keitel, V., Kelm, J. M., Kevin Park, B., Kordes, C., Kullak-Ublick, G. A., Lecluyse, E. L., Lu, P., Luebke-Wheeler, J., Lutz, A., Maltman, D. J., Matz-Soja, M., McMullen, P., Merfort, I., Messner, S., Meyer, C., Mwinyi, J., Naisbitt, D. J., Nussler, A. K., Olinga, P., Pampaloni, F., Pi, J., Pluta, L., Przyborski, S. A., Ramachandran, A., Rogiers, V., Rowe, C., Schelcher, C., Schmich, K., Schwarz, M., Singh, B., Stelzer, E. H. K., Stieger, B., Stöber, R., Sugiyama, Y., Tetta, C., Thasler, W. E., Vanhaecke, T., Vinken, M., Weiss, T. S., Widera, A., Woods, C. G., Xu, J. J., Yarborough, K. M. & Hengstler, J. G. Aug 2013 In : Archives of Toxicology. 87, 8, p. 1315-1530 216 p.

Research output: Contribution to journalArticle

Cell signaling
Liver
Hepatocytes
Metabolism
Drug interactions
7 Citations

Toxicogenomics for transcription factor-governed molecular pathways: Moving on to roles beyond classification and prediction

Andersen, M. E., McMullen, P. D. & Bhattacharya, S. Jan 2013 In : Archives of Toxicology. 87, 1, p. 7-11 5 p.

Research output: Contribution to journalArticle

Toxicogenetics
Gene Expression Regulation
Xenobiotics
Transcription Factors
71 Citations

Ultrasensitive response motifs: Basic amplifiers in molecular signalling networks

Zhang, Q., Bhattacharya, S. & Andersen, M. E. 2013 In : Open Biology. 3, APR, 130031

Research output: Contribution to journalArticle

Nonlinear Dynamics
Gene Regulatory Networks
Sigmoid Colon
Periodicity
Signal Transduction
2012
35 Citations

Modeling drug- and chemical-induced hepatotoxicity with systems biology approaches

Bhattacharya, S., Shoda, L. K. M., Zhang, Q., Woods, C. G., Howell, B. A., Siler, S. Q., Woodhead, J. L., Yang, Y., McMullen, P., Watkins, P. B. & Melvin, E. A. 2012 In : Frontiers in Physiology. 3 DEC, Article 462

Research output: Contribution to journalArticle

Systems Biology
Drug Design
Liver
Chemical and Drug Induced Liver Injury
Chemical Safety
2011
52 Citations

A deterministic map of Waddington's epigenetic landscape for cell fate specification

Bhattacharya, S., Zhang, Q. & Andersen, M. E. May 27 2011 In : BMC Systems Biology. 5, 85

Research output: Contribution to journalArticle

Epigenomics
Gene Regulatory Networks
Cell Lineage
Genes
Specification
113 Citations

Toxicity testing in the 21st century: Defining new risk assessment approaches based on perturbation of intracellular toxicity pathways

Bhattacharya, S., Zhang, Q., Carmichael, P. L., Boekelheide, K. & Andersen, M. E. 2011 In : PLoS One. 6, 6, e20887

Research output: Contribution to journalArticle

risk assessment process
toxicity testing
Risk assessment
Toxicity
European Union
2010
25 Citations

A bistable switch underlying B-cell differentiation and its disruption by the environmental contaminant 2,3,7,8-Tetrachlorodibenzo-p-dioxin

Bhattacharya, S., Conolly, R. B., Kaminski, N. E., Thomas, R. S., Andersen, M. E. & Zhang, Q. May 2010 In : Toxicological Sciences. 115, 1, p. 51-65 15 p.

Research output: Contribution to journalArticle

Cell Differentiation
B-Lymphocytes
Cells
Switches
Impurities
37 Citations

Computational systems biology and dose-response modeling in relation to new directions in toxicity testing

Zhang, Q., Bhattacharya, S., Andersen, M. E. & Conolly, R. B. Feb 2010 In : Journal of Toxicology and Environmental Health - Part B: Critical Reviews. 13, 2-4, p. 253-276 24 p.

Research output: Contribution to journalArticle

Systems Biology
Biological Science Disciplines
Computational Biology
Computer Simulation
Toxicity
15 Citations

Stochastic modeling of b lymphocyte terminal differentiation and its suppression by dioxin

Zhang, Q., Bhattacharya, S., Kline, D. E., Crawford, R. B., Conolly, R. B., Thomas, R. S., Kaminski, N. E. & Andersen, M. E. Apr 1 2010 In : BMC Systems Biology. 4, 40

Research output: Contribution to journalArticle

Dioxins
Stochastic Modeling
Lymphocytes
B Cells
B-Lymphocytes
2008
22 Citations
Silicic Acid
Polycondensation
Silicon Dioxide
Molecular dynamics
Gels
2005
26 Citations

Fractal dimensions of silica gels generated using reactive molecular dynamics simulations

Bhattacharya, S. & Kieffer, J. 2005 In : Journal of Chemical Physics. 122, 9, 094715

Research output: Contribution to journalArticle

Silica Gel
silica gel
Fractal dimension
Silicon Dioxide
Molecular dynamics