Profile The profile is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 6 Similar Profiles
Adenoviridae Medicine & Life Sciences
Vaccines Medicine & Life Sciences
Innate Immunity Medicine & Life Sciences
Antigens Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Adaptive Immunity Medicine & Life Sciences
Genes Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Grants 2015 2017

Publications 2009 2017

Decreased vector gene expression from e2b gene-deleted adenovirus serotype 5 vaccines intensifies proinflammatory immune responses

Quiroga, D., Aldhamen, Y. A., Godbehere, S., Harding, L. & Amalfitano, A. Jun 1 2017 In : Clinical and Vaccine Immunology. 24, 6, e00061-17

Research output: Contribution to journalArticle

Gene Expression
2 Citations

In vivo synthesis of cyclic-di-GMP using a recombinant adenovirus preferentially improves adaptive immune responses against extracellular antigens

Alyaqoub, F. S., Aldhamen, Y. A., Koestler, B. J., Bruger, E. L., Seregin, S. S., Pereira-Hicks, C., Godbehere, S., Waters, C. M. & Amalfitano, A. Feb 15 2016 In : Journal of Immunology. 196, 4, p. 1741-1752 12 p.

Research output: Contribution to journalArticle

Cyclic GMP
Adaptive Immunity
2 Citations

Long-term, high-level hepatic secretion of acid α-glucosidase for Pompe disease achieved in non-human primates using helper-dependent adenovirus

Rastall, D. P. W., Seregin, S. S., Aldhamen, Y. A., Kaiser, L. M., Mullins, C., Liou, A., Ing, F., Pereria-Hicks, C., Godbehere-Roosa, S., Palmer, D., Ng, P. & Amalfitano, A. Jul 21 2016 In : Gene Therapy.

Research output: Contribution to journalArticle

Glycogen Storage Disease Type II

Methods to Mitigate Immune Responses to Adenoviral Vectors

Aldhamen, Y. A. & Amalfitano, A. Apr 6 2016 Adenoviral Vectors for Gene Therapy: Second Edition. Elsevier Inc., p. 391-422 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Gene transfer
Genetic Therapy
6 Citations

Autoimmune disease-associated variants of extracellular endoplasmic reticulum aminopeptidase 1 induce altered innate immune responses by human immune cells

Aldhamen, Y. A., Pepelyayeva, Y., Rastall, D. P. W., Seregin, S. S., Zervoudi, E., Koumantou, D., Aylsworth, C. F., Quiroga, D., Godbehere, S., Georgiadis, D., Stratikos, E. & Amalfitano, A. May 6 2015 In : Journal of Innate Immunity. 7, 3, p. 275-289 15 p.

Research output: Contribution to journalArticle

Innate Immunity
Endoplasmic Reticulum
Autoimmune Diseases
Blood Cells