A molecular lock-and-key approach to detecting solution phase self-assembly. A fluorescence and absorption study of carminic acid in aqueous glucose solutions

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Abstract

We introduce a novel approach to the study of complex ternary systems where a fluorescent chromophore contains a functionality that incorporates into precrystalline aggregates in concentrated solutions. We demonstrate the feasibility of this approach by using carminic acid, a fluorescent molecule possessing a pendant glycosyl moiety, in aqueous glucose solutions. We report the steady state absorption and emission response of carminic acid as well as its picosecond dynamical response. These data, taken collectively, show that saturated glucose solutions exhibit anomalous molecular scale organization and that the persistence time of this organization is significantly less than a nanosecond. Our results indicate that kinetic contributions to crystallization are expected to play an important, sometimes dominant, role in this technologically important process.

LanguageEnglish (US)
Pages7220-7229
Number of pages10
JournalJournal of Physical Chemistry
Volume100
Issue number17
StatePublished - Apr 25 1996

Profile

Carmine
glucose
Self assembly
Glucose
self assembly
Fluorescence
fluorescence
acids
Acids
Ternary systems
Chromophores
ternary systems
Crystallization
chromophores
crystallization
Molecules
Kinetics
kinetics
molecules

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry

Cite this

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abstract = "We introduce a novel approach to the study of complex ternary systems where a fluorescent chromophore contains a functionality that incorporates into precrystalline aggregates in concentrated solutions. We demonstrate the feasibility of this approach by using carminic acid, a fluorescent molecule possessing a pendant glycosyl moiety, in aqueous glucose solutions. We report the steady state absorption and emission response of carminic acid as well as its picosecond dynamical response. These data, taken collectively, show that saturated glucose solutions exhibit anomalous molecular scale organization and that the persistence time of this organization is significantly less than a nanosecond. Our results indicate that kinetic contributions to crystallization are expected to play an important, sometimes dominant, role in this technologically important process.",
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