A novel process for recovery of fermentation-derived succinic acid

Alvaro Orjuela, Abraham J. Yanez, Lars Peereboom, Carl T. Lira, Dennis J. Miller

    Research output: Contribution to journalArticle

    • 23 Citations

    Abstract

    A novel approach to recover succinic acid from fermentation broth via acidification and esterification in ethanol is presented. Acid salts from fermentation are placed in ethanol along with a slight stoichiometric excess of sulfuric acid. Simultaneous acidification and esterification take place, with the inorganic sulfate salt formed precipitating out of the ethanol solution. The succinate is recovered as a solution of free succinic acid, monoethyl succinate, and diethyl succinate in ethanol, a mixture suitable for further esterification via reactive distillation. Recoveries of succinate species in excess of 95% were obtained for both model succinate salt solutions and for actual fermentation broth mixtures.

    Original languageEnglish (US)
    Pages (from-to)31-37
    Number of pages7
    JournalSeparation and Purification Technology
    Volume83
    Issue number1
    DOIs
    StatePublished - Nov 15 2011

    Profile

    Fermentation
    Ethanol
    Acids
    Esterification
    Salts
    Acidification
    Recovery
    Chronic Hepatitis
    Fluorinated Steroids
    Agglutination Tests
    Muscle Contraction
    Sulfuric acid
    Distillation
    Anthralin

    Keywords

    • Diethyl succinate
    • Esterification
    • Recovery
    • Sodium succinate
    • Succinic acid

    ASJC Scopus subject areas

    • Analytical Chemistry
    • Filtration and Separation

    Cite this

    A novel process for recovery of fermentation-derived succinic acid. / Orjuela, Alvaro; Yanez, Abraham J.; Peereboom, Lars; Lira, Carl T.; Miller, Dennis J.

    In: Separation and Purification Technology, Vol. 83, No. 1, 15.11.2011, p. 31-37.

    Research output: Contribution to journalArticle

    Orjuela, Alvaro; Yanez, Abraham J.; Peereboom, Lars; Lira, Carl T.; Miller, Dennis J. / A novel process for recovery of fermentation-derived succinic acid.

    In: Separation and Purification Technology, Vol. 83, No. 1, 15.11.2011, p. 31-37.

    Research output: Contribution to journalArticle

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