A novel process for recovery of fermentation-derived succinic acid: Process design and economic analysis

Alvaro Orjuela, Andrea Orjuela, Carl T. Lira, Dennis J. Miller

    Research output: Research - peer-reviewArticle

    • 19 Citations

    Abstract

    Recovery and purification of organic acids produced in fermentation constitutes a significant fraction of total production cost. In this paper, the design and economic analysis of a process to recover succinic acid (SA) via dissolution and acidification of succinate salts in ethanol, followed by reactive distillation to form succinate esters, is presented. Process simulation was performed for a range of plant capacities (13-55million kg/yr SA) and SA fermentation titers (50-100kg/m3). Economics were evaluated for a recovery system installed within an existing fermentation facility producing succinate salts at a cost of $0.66/kg SA. For a SA processing capacity of 54.9millionkg/yr and a titer of 100kg/m3 SA, the model predicts a capital investment of $75 million and a net processing cost of $1.85 per kg SA. Required selling price of diethyl succinate for a 30% annual return on investment is $1.57 per kg.

    LanguageEnglish (US)
    Pages235-241
    Number of pages7
    JournalBioresource Technology
    Volume139
    DOIs
    StatePublished - Jul 2013

    Profile

    Economic analysis
    Fermentation
    Process design
    Recovery
    Acids
    Succinic Acid
    economic analysis
    fermentation
    acid
    Economics
    Costs
    Costs and Cost Analysis
    Salts
    Processing
    salt
    cost
    Acidification
    Organic acids
    Distillation
    Purification

    Keywords

    • Esterification
    • Process economics
    • Reactive distillation
    • Recovery
    • Succinic acid

    ASJC Scopus subject areas

    • Bioengineering
    • Environmental Engineering
    • Waste Management and Disposal
    • Medicine(all)

    Cite this

    A novel process for recovery of fermentation-derived succinic acid : Process design and economic analysis. / Orjuela, Alvaro; Orjuela, Andrea; Lira, Carl T.; Miller, Dennis J.

    In: Bioresource Technology, Vol. 139, 07.2013, p. 235-241.

    Research output: Research - peer-reviewArticle

    @article{9c3e7d60de034966974be1bef8e8a59e,
    title = "A novel process for recovery of fermentation-derived succinic acid: Process design and economic analysis",
    abstract = "Recovery and purification of organic acids produced in fermentation constitutes a significant fraction of total production cost. In this paper, the design and economic analysis of a process to recover succinic acid (SA) via dissolution and acidification of succinate salts in ethanol, followed by reactive distillation to form succinate esters, is presented. Process simulation was performed for a range of plant capacities (13-55million kg/yr SA) and SA fermentation titers (50-100kg/m3). Economics were evaluated for a recovery system installed within an existing fermentation facility producing succinate salts at a cost of $0.66/kg SA. For a SA processing capacity of 54.9millionkg/yr and a titer of 100kg/m3 SA, the model predicts a capital investment of $75 million and a net processing cost of $1.85 per kg SA. Required selling price of diethyl succinate for a 30% annual return on investment is $1.57 per kg.",
    keywords = "Esterification, Process economics, Reactive distillation, Recovery, Succinic acid",
    author = "Alvaro Orjuela and Andrea Orjuela and Lira, {Carl T.} and Miller, {Dennis J.}",
    year = "2013",
    month = "7",
    doi = "10.1016/j.biortech.2013.03.174",
    volume = "139",
    pages = "235--241",
    journal = "Bioresource Technology",
    issn = "0960-8524",
    publisher = "Elsevier Limited",

    }

    TY - JOUR

    T1 - A novel process for recovery of fermentation-derived succinic acid

    T2 - Bioresource Technology

    AU - Orjuela,Alvaro

    AU - Orjuela,Andrea

    AU - Lira,Carl T.

    AU - Miller,Dennis J.

    PY - 2013/7

    Y1 - 2013/7

    N2 - Recovery and purification of organic acids produced in fermentation constitutes a significant fraction of total production cost. In this paper, the design and economic analysis of a process to recover succinic acid (SA) via dissolution and acidification of succinate salts in ethanol, followed by reactive distillation to form succinate esters, is presented. Process simulation was performed for a range of plant capacities (13-55million kg/yr SA) and SA fermentation titers (50-100kg/m3). Economics were evaluated for a recovery system installed within an existing fermentation facility producing succinate salts at a cost of $0.66/kg SA. For a SA processing capacity of 54.9millionkg/yr and a titer of 100kg/m3 SA, the model predicts a capital investment of $75 million and a net processing cost of $1.85 per kg SA. Required selling price of diethyl succinate for a 30% annual return on investment is $1.57 per kg.

    AB - Recovery and purification of organic acids produced in fermentation constitutes a significant fraction of total production cost. In this paper, the design and economic analysis of a process to recover succinic acid (SA) via dissolution and acidification of succinate salts in ethanol, followed by reactive distillation to form succinate esters, is presented. Process simulation was performed for a range of plant capacities (13-55million kg/yr SA) and SA fermentation titers (50-100kg/m3). Economics were evaluated for a recovery system installed within an existing fermentation facility producing succinate salts at a cost of $0.66/kg SA. For a SA processing capacity of 54.9millionkg/yr and a titer of 100kg/m3 SA, the model predicts a capital investment of $75 million and a net processing cost of $1.85 per kg SA. Required selling price of diethyl succinate for a 30% annual return on investment is $1.57 per kg.

    KW - Esterification

    KW - Process economics

    KW - Reactive distillation

    KW - Recovery

    KW - Succinic acid

    UR - http://www.scopus.com/inward/record.url?scp=84877808154&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=84877808154&partnerID=8YFLogxK

    U2 - 10.1016/j.biortech.2013.03.174

    DO - 10.1016/j.biortech.2013.03.174

    M3 - Article

    VL - 139

    SP - 235

    EP - 241

    JO - Bioresource Technology

    JF - Bioresource Technology

    SN - 0960-8524

    ER -