Application of metabolic engineering to cellular processes of the liver: Bioartificial liver development

Christina Chan, Junji Washizu, Francois Berthiaume, Mehmet Toner, Martin L. Yarmush

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The effect of insulin pre-conditioning and amino acid supplementation on the accumulation of lipids was investigated. Hepatocytes were cultured in the collagen sandwich configuration in culture medium for six days prior to exposing the cells to plasma to allow recovery from the isolation. Metabolic flux analysis (MFA) was used to quantify the changes in lipogenic fluxes and pathways within the cells.

Original languageEnglish (US)
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
EditorsR.D. Kamm, G.W. Schmid-Schoenbein, G.A. Atesian, M.S. Hefzy
Pages357-358
Number of pages2
Volume50
StatePublished - 2001
Externally publishedYes
EventProceedings of the 2001 Bioengineering Conference - Snowbird, UT, United States

Other

OtherProceedings of the 2001 Bioengineering Conference
CountryUnited States
CitySnowbird, UT
Period6/27/017/1/01

Profile

Liver
Fluxes
Metabolic engineering
Insulin
Collagen
Lipids
Amino acids
Plasmas
Recovery

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Chan, C., Washizu, J., Berthiaume, F., Toner, M., & Yarmush, M. L. (2001). Application of metabolic engineering to cellular processes of the liver: Bioartificial liver development. In R. D. Kamm, G. W. Schmid-Schoenbein, G. A. Atesian, & M. S. Hefzy (Eds.), American Society of Mechanical Engineers, Bioengineering Division (Publication) BED (Vol. 50, pp. 357-358)

Application of metabolic engineering to cellular processes of the liver : Bioartificial liver development. / Chan, Christina; Washizu, Junji; Berthiaume, Francois; Toner, Mehmet; Yarmush, Martin L.

American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. ed. / R.D. Kamm; G.W. Schmid-Schoenbein; G.A. Atesian; M.S. Hefzy. Vol. 50 2001. p. 357-358.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Chan, C, Washizu, J, Berthiaume, F, Toner, M & Yarmush, ML 2001, Application of metabolic engineering to cellular processes of the liver: Bioartificial liver development. in RD Kamm, GW Schmid-Schoenbein, GA Atesian & MS Hefzy (eds), American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. vol. 50, pp. 357-358, Proceedings of the 2001 Bioengineering Conference, Snowbird, UT, United States, 27-1 July.
Chan C, Washizu J, Berthiaume F, Toner M, Yarmush ML. Application of metabolic engineering to cellular processes of the liver: Bioartificial liver development. In Kamm RD, Schmid-Schoenbein GW, Atesian GA, Hefzy MS, editors, American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol. 50. 2001. p. 357-358.

Chan, Christina; Washizu, Junji; Berthiaume, Francois; Toner, Mehmet; Yarmush, Martin L. / Application of metabolic engineering to cellular processes of the liver : Bioartificial liver development.

American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. ed. / R.D. Kamm; G.W. Schmid-Schoenbein; G.A. Atesian; M.S. Hefzy. Vol. 50 2001. p. 357-358.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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