Biomedical and clinical networks of cancer

Ertugrul Dalkic, Christina Chan

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Cancer is a large class of diseases. Systems level analysis of complex diseases such as cancer requires the analysis of relationships between different types of clinical as well as molecular data. Chemotherapy, in addition to radiotherapy and surgery, is used to treat cancers. However, cancer drugs mostly target general processes, i.e. DNA synthesis, toinhibit cell division. A recent trend has been to use targeted chemotherapy, to more selectively treat specific types of cancer. Systems science is the analysis of the global organization of the relationships between groups, i.e. the different types of diseases and drugs, and is in contrast to traditional approaches of analyzing individual parts of a system. Such analyses have provided an understanding of the combined clinical and molecular aspects of diseases such as cancer. Networks of diseases, drugs, and genes showed unexpected connectivity for particular members, correlations between the connectivity with epidemiological features, etc. Network analysis of clinical, medical and molecular data is a promising branch of systems science.

LanguageEnglish (US)
Title of host publicationNetwork Topologies: Types, Performance Impact and Advantages/Disadvantages
PublisherNova Science Publishers, Inc.
Pages131-140
Number of pages10
ISBN (Print)9781626181809
StatePublished - 2013

Profile

Systems science
Chemotherapy
Radiotherapy
Electric network analysis
Surgery
DNA
Genes
Cells

ASJC Scopus subject areas

  • Computer Science(all)

Cite this

Dalkic, E., & Chan, C. (2013). Biomedical and clinical networks of cancer. In Network Topologies: Types, Performance Impact and Advantages/Disadvantages (pp. 131-140). Nova Science Publishers, Inc..

Biomedical and clinical networks of cancer. / Dalkic, Ertugrul; Chan, Christina.

Network Topologies: Types, Performance Impact and Advantages/Disadvantages. Nova Science Publishers, Inc., 2013. p. 131-140.

Research output: Chapter in Book/Report/Conference proceedingChapter

Dalkic, E & Chan, C 2013, Biomedical and clinical networks of cancer. in Network Topologies: Types, Performance Impact and Advantages/Disadvantages. Nova Science Publishers, Inc., pp. 131-140.
Dalkic E, Chan C. Biomedical and clinical networks of cancer. In Network Topologies: Types, Performance Impact and Advantages/Disadvantages. Nova Science Publishers, Inc.2013. p. 131-140.
Dalkic, Ertugrul ; Chan, Christina. / Biomedical and clinical networks of cancer. Network Topologies: Types, Performance Impact and Advantages/Disadvantages. Nova Science Publishers, Inc., 2013. pp. 131-140
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