Biomedical and clinical networks of cancer

Ertugrul Dalkic, Christina Chan

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Abstract

    Cancer is a large class of diseases. Systems level analysis of complex diseases such as cancer requires the analysis of relationships between different types of clinical as well as molecular data. Chemotherapy, in addition to radiotherapy and surgery, is used to treat cancers. However, cancer drugs mostly target general processes, i.e. DNA synthesis, toinhibit cell division. A recent trend has been to use targeted chemotherapy, to more selectively treat specific types of cancer. Systems science is the analysis of the global organization of the relationships between groups, i.e. the different types of diseases and drugs, and is in contrast to traditional approaches of analyzing individual parts of a system. Such analyses have provided an understanding of the combined clinical and molecular aspects of diseases such as cancer. Networks of diseases, drugs, and genes showed unexpected connectivity for particular members, correlations between the connectivity with epidemiological features, etc. Network analysis of clinical, medical and molecular data is a promising branch of systems science.

    Original languageEnglish (US)
    Title of host publicationNetwork Topologies: Types, Performance Impact and Advantages/Disadvantages
    PublisherNova Science Publishers, Inc.
    Pages131-140
    Number of pages10
    ISBN (Print)9781626181809
    StatePublished - 2013

    Profile

    Systems science
    Chemotherapy
    Radiotherapy
    Electric network analysis
    Surgery
    DNA
    Genes
    Cells

    ASJC Scopus subject areas

    • Computer Science(all)

    Cite this

    Dalkic, E., & Chan, C. (2013). Biomedical and clinical networks of cancer. In Network Topologies: Types, Performance Impact and Advantages/Disadvantages (pp. 131-140). Nova Science Publishers, Inc..

    Biomedical and clinical networks of cancer. / Dalkic, Ertugrul; Chan, Christina.

    Network Topologies: Types, Performance Impact and Advantages/Disadvantages. Nova Science Publishers, Inc., 2013. p. 131-140.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Dalkic, E & Chan, C 2013, Biomedical and clinical networks of cancer. in Network Topologies: Types, Performance Impact and Advantages/Disadvantages. Nova Science Publishers, Inc., pp. 131-140.
    Dalkic E, Chan C. Biomedical and clinical networks of cancer. In Network Topologies: Types, Performance Impact and Advantages/Disadvantages. Nova Science Publishers, Inc.2013. p. 131-140.

    Dalkic, Ertugrul; Chan, Christina / Biomedical and clinical networks of cancer.

    Network Topologies: Types, Performance Impact and Advantages/Disadvantages. Nova Science Publishers, Inc., 2013. p. 131-140.

    Research output: Chapter in Book/Report/Conference proceedingChapter

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