Catalytic upgrading of fermentation-derived organic acids

Sriram Varadarajan, Dennis J. Miller

    Research output: Contribution to journalArticle

    • 124 Citations

    Abstract

    The production of organic acids in low-cost, high-efficiency fermentation processes makes available a new route to chemical production from biomass. Because of their multiple functional groups and high reactivity, organic acids can undergo a variety of reactions that are effectively catalyzed by inorganic heterogeneous or homogeneous catalysts. Lactic acid and succinic acid, in particular, are approaching large-scale production via fermentation and show excellent promise as feedstocks for catalytic conversion routes such as hydrogenation, dehydration, or condensation. A number of catalytic conversion pathways of organic acids are potentially competitive with petroleum-based routes in the current economic environment, particularly when integrated into existing biomass/crop processing schemes. This article reviews some of the key reaction pathways available using fermentation-derived organic acids as feedstocks and presents recent results from the authors' lab on succinate hydrogenation to 1,4-butanediol and tetrahydrofuran. By a judicious choice of support properties and reaction conditions, it is possible to achieve yields of either of these two products in excess of 80%.

    Original languageEnglish (US)
    Pages (from-to)845-854
    Number of pages10
    JournalBiotechnology Progress
    Volume15
    Issue number5
    DOIs
    StatePublished - Sep 17 1999

    Profile

    Fermentation
    Acids
    organic acids and salts
    fermentation
    Hydrogenation
    Succinic Acid
    Biomass
    hydrogenation
    succinic acid
    feedstocks
    Butylene Glycols
    Petroleum
    Dehydration
    Lactic Acid
    Economics
    Costs and Cost Analysis
    butanediol
    energy crops
    catalysts
    petroleum

    ASJC Scopus subject areas

    • Food Science
    • Biotechnology
    • Microbiology

    Cite this

    Catalytic upgrading of fermentation-derived organic acids. / Varadarajan, Sriram; Miller, Dennis J.

    In: Biotechnology Progress, Vol. 15, No. 5, 17.09.1999, p. 845-854.

    Research output: Contribution to journalArticle

    Varadarajan, Sriram; Miller, Dennis J. / Catalytic upgrading of fermentation-derived organic acids.

    In: Biotechnology Progress, Vol. 15, No. 5, 17.09.1999, p. 845-854.

    Research output: Contribution to journalArticle

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