Corn stover semi-mechanistic enzymatic hydrolysis model with tight parameter confidence intervals for model-based process design and optimization

Felipe Scott, Muyang Li, Daniel L. Williams, Raúl Conejeros, David B. Hodge, Germán Aroca

    Research output: Contribution to journalArticle

    • 3 Citations

    Abstract

    Uncertainty associated to the estimated values of the parameters in a model is a key piece of information for decision makers and model users. However, this information is typically not reported or the confidence intervals are too large to be useful. A semi-mechanistic model for the enzymatic saccharification of dilute acid pretreated corn stover is proposed in this work, the model is a modification of an existing one providing a statistically significant improved fit towards a set of experimental data that includes varying initial solid loadings (10-25% w/w) and the use of the pretreatment liquor and washed solids with or without supplementation of key inhibitors. A subset of 8 out of 17 parameters was identified, showing sufficiently tight confidence intervals to be used in uncertainty propagation and model analysis, without requiring interval truncation via expert judgment.

    Original languageEnglish (US)
    Pages (from-to)255-265
    Number of pages11
    JournalBioresource Technology
    Volume177
    DOIs
    StatePublished - Feb 1 2015

    Profile

    Zea mays
    Uncertainty
    Hydrolysis
    Confidence Intervals
    Anthralin
    Acids
    Datasets
    confidence interval
    Butylene Glycols
    maize
    Avian Crop
    Phleomycins
    Enzymatic hydrolysis
    Basement Membrane
    inhibitor
    hydrolysis
    acid
    Saccharification
    Process design

    Keywords

    • Biofuels
    • Enzymatic hydrolysis
    • High-solids saccharification
    • Kinetic model
    • Lignocellulose

    ASJC Scopus subject areas

    • Bioengineering
    • Environmental Engineering
    • Waste Management and Disposal
    • Medicine(all)

    Cite this

    Corn stover semi-mechanistic enzymatic hydrolysis model with tight parameter confidence intervals for model-based process design and optimization. / Scott, Felipe; Li, Muyang; Williams, Daniel L.; Conejeros, Raúl; Hodge, David B.; Aroca, Germán.

    In: Bioresource Technology, Vol. 177, 01.02.2015, p. 255-265.

    Research output: Contribution to journalArticle

    Scott, Felipe; Li, Muyang; Williams, Daniel L.; Conejeros, Raúl; Hodge, David B.; Aroca, Germán / Corn stover semi-mechanistic enzymatic hydrolysis model with tight parameter confidence intervals for model-based process design and optimization.

    In: Bioresource Technology, Vol. 177, 01.02.2015, p. 255-265.

    Research output: Contribution to journalArticle

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    AU - Hodge,David B.

    AU - Aroca,Germán

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