Diethyl succinate synthesis by reactive distillation

Alvaro Orjuela, Aspi Kolah, Xi Hong, Carl T. Lira, Dennis J. Miller

    Research output: Contribution to journalArticle

    • 17 Citations

    Abstract

    Diethyl succinate is continuously produced from succinic acid and ethanol in a 6-m tall, elevated pressure reactive distillation column. Esterification is carried out in excess ethanol such that water and ethanol are produced in the distillate and diethyl succinate is produced in the bottoms stream. The reaction is catalyzed by Amberlyst 70 cation exchange resin contained in KATAPAK SP-11® structured packing within the stainless steel column. Succinic acid conversions approaching 100%, and diethyl succinate yields of up to 98% have been experimentally achieved in the lab scale column. The esterification process has been simulated using the Radfrac module in Aspen Plus®. Simulations used reaction kinetic and phase equilibrium data collected in our laboratory to predict the steady state stream compositions from the column. Good agreement between experimental and simulation results was observed, thus facilitating the use of the model for design and scale up of the reactive distillation process.

    Original languageEnglish (US)
    Pages (from-to)151-162
    Number of pages12
    JournalSeparation and Purification Technology
    Volume88
    DOIs
    StatePublished - Mar 22 2012

    Profile

    Ethanol
    Esterification
    Distillation
    Acids
    Chronic Hepatitis
    Distillation columns
    Reaction kinetics
    Phase equilibria
    Ion exchange
    Stainless steel
    Resins
    Positive ions
    Chemical analysis
    Water
    African horse sickness virus
    Cutaneous Candidiasis
    Acromion
    Anthralin
    Erythrocyte Deformability
    Cytophotometry

    Keywords

    • Diethyl succinate
    • Esterification
    • Monoethyl succinate
    • Reactive distillation
    • Succinic acid

    ASJC Scopus subject areas

    • Analytical Chemistry
    • Filtration and Separation

    Cite this

    Diethyl succinate synthesis by reactive distillation. / Orjuela, Alvaro; Kolah, Aspi; Hong, Xi; Lira, Carl T.; Miller, Dennis J.

    In: Separation and Purification Technology, Vol. 88, 22.03.2012, p. 151-162.

    Research output: Contribution to journalArticle

    Orjuela, Alvaro; Kolah, Aspi; Hong, Xi; Lira, Carl T.; Miller, Dennis J. / Diethyl succinate synthesis by reactive distillation.

    In: Separation and Purification Technology, Vol. 88, 22.03.2012, p. 151-162.

    Research output: Contribution to journalArticle

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