Gene and Protein Expression - Modeling Nested Motifs in Cellular and Tissue Response Networks

Melvin E. Andersen, Qiang Zhang, Sudin Bhattacharya

Research output: ResearchChapter

  • 1 Citations
LanguageEnglish (US)
Title of host publicationQuantitative Modeling in Toxicology
PublisherJohn Wiley and Sons
Pages219-233
Number of pages15
ISBN (Print)9780470998090
DOIs
StatePublished - Mar 30 2010
Externally publishedYes

Keywords

  • (Feed Forward Loop) (FFL) motifs - in transcriptional networks in organisms
  • Bistability in double-negative feedback loop motif - visually represented by "bifurcation diagram"
  • Cell signaling mechanisms - receptor auto-induction and mitogen-activated protein kinase (MAPK) cascades
  • Cusp catastrophe surface for double-negative feedback loop motif
  • Gene and protein expression - modeling nested motifs in cellular and tissue response networks
  • Modeling approaches for toxicology and risk assessment problems
  • Modeling motifs and transcriptional networks
  • Receptor-mediated and non-receptor-mediated toxicity - blurring considerably
  • Transcriptional Networks (TNs)
  • Transcriptional responses of cells and tissues to chemical exposures

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Andersen, M. E., Zhang, Q., & Bhattacharya, S. (2010). Gene and Protein Expression - Modeling Nested Motifs in Cellular and Tissue Response Networks. In Quantitative Modeling in Toxicology (pp. 219-233). John Wiley and Sons. DOI: 10.1002/9780470686263.ch10

Gene and Protein Expression - Modeling Nested Motifs in Cellular and Tissue Response Networks. / Andersen, Melvin E.; Zhang, Qiang; Bhattacharya, Sudin.

Quantitative Modeling in Toxicology. John Wiley and Sons, 2010. p. 219-233.

Research output: ResearchChapter

Andersen, ME, Zhang, Q & Bhattacharya, S 2010, Gene and Protein Expression - Modeling Nested Motifs in Cellular and Tissue Response Networks. in Quantitative Modeling in Toxicology. John Wiley and Sons, pp. 219-233. DOI: 10.1002/9780470686263.ch10
Andersen ME, Zhang Q, Bhattacharya S. Gene and Protein Expression - Modeling Nested Motifs in Cellular and Tissue Response Networks. In Quantitative Modeling in Toxicology. John Wiley and Sons. 2010. p. 219-233. Available from, DOI: 10.1002/9780470686263.ch10
Andersen, Melvin E. ; Zhang, Qiang ; Bhattacharya, Sudin. / Gene and Protein Expression - Modeling Nested Motifs in Cellular and Tissue Response Networks. Quantitative Modeling in Toxicology. John Wiley and Sons, 2010. pp. 219-233
@inbook{aa03753bb2ca4629a332d4f1fdae458c,
title = "Gene and Protein Expression - Modeling Nested Motifs in Cellular and Tissue Response Networks",
keywords = "(Feed Forward Loop) (FFL) motifs - in transcriptional networks in organisms, Bistability in double-negative feedback loop motif - visually represented by {"}bifurcation diagram{"}, Cell signaling mechanisms - receptor auto-induction and mitogen-activated protein kinase (MAPK) cascades, Cusp catastrophe surface for double-negative feedback loop motif, Gene and protein expression - modeling nested motifs in cellular and tissue response networks, Modeling approaches for toxicology and risk assessment problems, Modeling motifs and transcriptional networks, Receptor-mediated and non-receptor-mediated toxicity - blurring considerably, Transcriptional Networks (TNs), Transcriptional responses of cells and tissues to chemical exposures",
author = "Andersen, {Melvin E.} and Qiang Zhang and Sudin Bhattacharya",
year = "2010",
month = "3",
doi = "10.1002/9780470686263.ch10",
isbn = "9780470998090",
pages = "219--233",
booktitle = "Quantitative Modeling in Toxicology",
publisher = "John Wiley and Sons",

}

TY - CHAP

T1 - Gene and Protein Expression - Modeling Nested Motifs in Cellular and Tissue Response Networks

AU - Andersen,Melvin E.

AU - Zhang,Qiang

AU - Bhattacharya,Sudin

PY - 2010/3/30

Y1 - 2010/3/30

KW - (Feed Forward Loop) (FFL) motifs - in transcriptional networks in organisms

KW - Bistability in double-negative feedback loop motif - visually represented by "bifurcation diagram"

KW - Cell signaling mechanisms - receptor auto-induction and mitogen-activated protein kinase (MAPK) cascades

KW - Cusp catastrophe surface for double-negative feedback loop motif

KW - Gene and protein expression - modeling nested motifs in cellular and tissue response networks

KW - Modeling approaches for toxicology and risk assessment problems

KW - Modeling motifs and transcriptional networks

KW - Receptor-mediated and non-receptor-mediated toxicity - blurring considerably

KW - Transcriptional Networks (TNs)

KW - Transcriptional responses of cells and tissues to chemical exposures

UR - http://www.scopus.com/inward/record.url?scp=77953988694&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77953988694&partnerID=8YFLogxK

U2 - 10.1002/9780470686263.ch10

DO - 10.1002/9780470686263.ch10

M3 - Chapter

SN - 9780470998090

SP - 219

EP - 233

BT - Quantitative Modeling in Toxicology

PB - John Wiley and Sons

ER -