In situ immobilization of palladium nanoparticles in microfluidic reactors and assessment of their catalytic activity

Rui Lin, Ruel G. Freemantle, Nicholas M. Kelly, Thomas R. Fielitz, Sherine O. Obare, Robert Y. Ofoli

    Research output: Contribution to journalArticle

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    Abstract

    We report on the synthesis and characterization of catalytic palladium nanoparticles (Pd NPs) and their immobilization in microfluidic reactors fabricated from polydimethylsiloxane (PDMS). The Pd NPs were stabilized with D-biotin or 3-aminopropyltrimethoxysilane (APTMS) to promote immobilization inside the microfluidic reactors. The NPs were homogeneous with narrow size distributions between 2 and 4 nm, and were characterized by transmission electron microscopy (TEM), selected-area electron diffraction (SAED), and x-ray diffraction (XRD). Biotinylated Pd NPs were immobilized on APTMS-modified PDMS and glass surfaces through the formation of covalent amide bonds between activated biotin and surface amino groups. By contrast, APTMS-stabilized Pd NPs were immobilized directly onto PDMS and glass surfaces rich in hydroxyl groups. Fourier transform infrared spectroscopy (FT-IR) and x-ray photoelectron spectroscopy (XPS) results showed successful attachment of both types of Pd NPs on glass and PDMS surfaces. Both types of Pd NPs were then immobilized in situ in sealed PDMS microfluidic reactors after similar surface modification. The effectiveness of immobilization in the microfluidic reactors was evaluated by hydrogenation of 6-bromo-1-hexene at room temperature and one atmosphere of hydrogen pressure. An average first-run conversion of 85% and selectivity of 100% were achieved in approximately 18 min of reaction time. Control experiments showed that no hydrogenation occurred in the absence of the nanocatalysts. This system has the potential to provide a reliable tool for efficient and high throughput evaluation of catalytic NPs, along with assessment of intrinsic kinetics.

    Original languageEnglish (US)
    Article number325605
    JournalNanotechnology
    Volume21
    Issue number32
    DOIs
    StatePublished - Jul 21 2010

    Profile

    Palladium
    Nanoparticles
    Myosins
    Polydimethylsiloxane
    Microfluidics
    Edema Disease of Swine
    Glass
    Hydrogenation
    X rays
    Parovarian Cyst
    Deoxyribonucleoproteins
    Photoelectron spectroscopy
    Amides
    Electron diffraction
    Fourier transform infrared spectroscopy
    Surface treatment
    Catalyst activity
    Diffraction
    Throughput
    Protective atmospheres

    ASJC Scopus subject areas

    • Bioengineering
    • Chemistry(all)
    • Electrical and Electronic Engineering
    • Mechanical Engineering
    • Mechanics of Materials
    • Materials Science(all)

    Cite this

    In situ immobilization of palladium nanoparticles in microfluidic reactors and assessment of their catalytic activity. / Lin, Rui; Freemantle, Ruel G.; Kelly, Nicholas M.; Fielitz, Thomas R.; Obare, Sherine O.; Ofoli, Robert Y.

    In: Nanotechnology, Vol. 21, No. 32, 325605, 21.07.2010.

    Research output: Contribution to journalArticle

    Lin, Rui; Freemantle, Ruel G.; Kelly, Nicholas M.; Fielitz, Thomas R.; Obare, Sherine O.; Ofoli, Robert Y. / In situ immobilization of palladium nanoparticles in microfluidic reactors and assessment of their catalytic activity.

    In: Nanotechnology, Vol. 21, No. 32, 325605, 21.07.2010.

    Research output: Contribution to journalArticle

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