Kinetics of the aqueous-phase hydrogenation of L-alanine to L-alaninol

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    Abstract

    The kinetics of the aqueous-phase, stereoretentive hydrogenation of alanine to alaninol over 5 wt % Ru/C catalyst in a three-phase stirred batch reactor is presented. Alanine readily undergoes hydrogenation when in the carboxylic acid form (-COOH), a condition that can be achieved by acidifying the reaction solution with phosphoric acid. The conversion rate is not limited by mass-transport resistances over the ranges of temperature (353-398 K), hydrogen pressure (1.7-13.8 MPa), alanine feed concentration (0.22-0.46 M), and phosphoric acid concentration (0-1.2M) investigated. A Langmuir-Hinshelwood (L-H) kinetic model is presented in which protonated alanine and undissociated phosphoric acid compete for one set of surface sites and H2 dissociatively adsorbs on a second type of site. The average error between the experimental and predicted conversions over all data collected was 8%.

    Original languageEnglish (US)
    Pages (from-to)3297-3303
    Number of pages7
    JournalIndustrial and Engineering Chemistry Research
    Volume43
    Issue number13
    StatePublished - Jun 23 2004

    Profile

    Phosphoric acid
    Hydrogenation
    Kinetics
    kinetics
    acid
    Alanine
    Acids
    Deoxyribonucleoproteins
    Batch reactors
    Carboxylic acids
    Mass transfer
    Hydrogen
    Catalysts
    Temperature
    carboxylic acid
    mass transport
    catalyst
    hydrogen
    temperature
    Carboxylic Acids

    ASJC Scopus subject areas

    • Polymers and Plastics
    • Environmental Science(all)
    • Chemical Engineering (miscellaneous)

    Cite this

    Kinetics of the aqueous-phase hydrogenation of L-alanine to L-alaninol. / Jere, Frank T.; Jackson, James E.; Miller, Dennis J.

    In: Industrial and Engineering Chemistry Research, Vol. 43, No. 13, 23.06.2004, p. 3297-3303.

    Research output: Contribution to journalArticle

    Jere, Frank T.; Jackson, James E.; Miller, Dennis J. / Kinetics of the aqueous-phase hydrogenation of L-alanine to L-alaninol.

    In: Industrial and Engineering Chemistry Research, Vol. 43, No. 13, 23.06.2004, p. 3297-3303.

    Research output: Contribution to journalArticle

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    abstract = "The kinetics of the aqueous-phase, stereoretentive hydrogenation of alanine to alaninol over 5 wt % Ru/C catalyst in a three-phase stirred batch reactor is presented. Alanine readily undergoes hydrogenation when in the carboxylic acid form (-COOH), a condition that can be achieved by acidifying the reaction solution with phosphoric acid. The conversion rate is not limited by mass-transport resistances over the ranges of temperature (353-398 K), hydrogen pressure (1.7-13.8 MPa), alanine feed concentration (0.22-0.46 M), and phosphoric acid concentration (0-1.2M) investigated. A Langmuir-Hinshelwood (L-H) kinetic model is presented in which protonated alanine and undissociated phosphoric acid compete for one set of surface sites and H2 dissociatively adsorbs on a second type of site. The average error between the experimental and predicted conversions over all data collected was 8%.",
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    N2 - The kinetics of the aqueous-phase, stereoretentive hydrogenation of alanine to alaninol over 5 wt % Ru/C catalyst in a three-phase stirred batch reactor is presented. Alanine readily undergoes hydrogenation when in the carboxylic acid form (-COOH), a condition that can be achieved by acidifying the reaction solution with phosphoric acid. The conversion rate is not limited by mass-transport resistances over the ranges of temperature (353-398 K), hydrogen pressure (1.7-13.8 MPa), alanine feed concentration (0.22-0.46 M), and phosphoric acid concentration (0-1.2M) investigated. A Langmuir-Hinshelwood (L-H) kinetic model is presented in which protonated alanine and undissociated phosphoric acid compete for one set of surface sites and H2 dissociatively adsorbs on a second type of site. The average error between the experimental and predicted conversions over all data collected was 8%.

    AB - The kinetics of the aqueous-phase, stereoretentive hydrogenation of alanine to alaninol over 5 wt % Ru/C catalyst in a three-phase stirred batch reactor is presented. Alanine readily undergoes hydrogenation when in the carboxylic acid form (-COOH), a condition that can be achieved by acidifying the reaction solution with phosphoric acid. The conversion rate is not limited by mass-transport resistances over the ranges of temperature (353-398 K), hydrogen pressure (1.7-13.8 MPa), alanine feed concentration (0.22-0.46 M), and phosphoric acid concentration (0-1.2M) investigated. A Langmuir-Hinshelwood (L-H) kinetic model is presented in which protonated alanine and undissociated phosphoric acid compete for one set of surface sites and H2 dissociatively adsorbs on a second type of site. The average error between the experimental and predicted conversions over all data collected was 8%.

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