Microbial lipid-based lignocellulosic biorefinery: Feasibility and challenges

Mingjie Jin, Patricia J. Slininger, Bruce S. Dien, Suresh Waghmode, Bryan R. Moser, Andrea Orjuela, Leonardo da Costa Sousa, Venkatesh Balan

Research output: Contribution to journalArticle

  • 65 Citations

Abstract

Although single-cell oil (SCO) has been studied for decades, lipid production from lignocellulosic biomass has received substantial attention only in recent years as biofuel research moves toward producing drop-in fuels. This review gives an overview of the feasibility and challenges that exist in realizing microbial lipid production from lignocellulosic biomass in a biorefinery. The aspects covered here include biorefinery technologies, the microbial oil market, oleaginous microbes, lipid accumulation metabolism, strain development, process configurations, lignocellulosic lipid production, technical hurdles, lipid recovery, and technoeconomics. The lignocellulosic SCO-based biorefinery will be feasible only if a combination of low- and high-value lipids are coproduced, while lignin and protein are upgraded to high-value products.

LanguageEnglish (US)
Pages43-54
Number of pages12
JournalTrends in Biotechnology
Volume33
Issue number1
DOIs
StatePublished - Jan 1 2015

Profile

Lipids
Oils
Biomass
Biofuels
Lignin
Lipid Metabolism
Metabolism
Technology
Proteins
Recovery
Research

Keywords

  • Biorefinery
  • Lignocellulosic lipids
  • Microbial lipids
  • Single-cell oil

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering

Cite this

Jin, M., Slininger, P. J., Dien, B. S., Waghmode, S., Moser, B. R., Orjuela, A., ... Balan, V. (2015). Microbial lipid-based lignocellulosic biorefinery: Feasibility and challenges. Trends in Biotechnology, 33(1), 43-54. DOI: 10.1016/j.tibtech.2014.11.005

Microbial lipid-based lignocellulosic biorefinery : Feasibility and challenges. / Jin, Mingjie; Slininger, Patricia J.; Dien, Bruce S.; Waghmode, Suresh; Moser, Bryan R.; Orjuela, Andrea; Sousa, Leonardo da Costa; Balan, Venkatesh.

In: Trends in Biotechnology, Vol. 33, No. 1, 01.01.2015, p. 43-54.

Research output: Contribution to journalArticle

Jin, M, Slininger, PJ, Dien, BS, Waghmode, S, Moser, BR, Orjuela, A, Sousa, LDC & Balan, V 2015, 'Microbial lipid-based lignocellulosic biorefinery: Feasibility and challenges' Trends in Biotechnology, vol 33, no. 1, pp. 43-54. DOI: 10.1016/j.tibtech.2014.11.005
Jin M, Slininger PJ, Dien BS, Waghmode S, Moser BR, Orjuela A et al. Microbial lipid-based lignocellulosic biorefinery: Feasibility and challenges. Trends in Biotechnology. 2015 Jan 1;33(1):43-54. Available from, DOI: 10.1016/j.tibtech.2014.11.005
Jin, Mingjie ; Slininger, Patricia J. ; Dien, Bruce S. ; Waghmode, Suresh ; Moser, Bryan R. ; Orjuela, Andrea ; Sousa, Leonardo da Costa ; Balan, Venkatesh. / Microbial lipid-based lignocellulosic biorefinery : Feasibility and challenges. In: Trends in Biotechnology. 2015 ; Vol. 33, No. 1. pp. 43-54
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