Microbial lipid-based lignocellulosic biorefinery: Feasibility and challenges

Mingjie Jin, Patricia J. Slininger, Bruce S. Dien, Suresh Waghmode, Bryan R. Moser, Andrea Orjuela, Leonardo da Costa Sousa, Venkatesh Balan

    Research output: Research - peer-reviewArticle

    • 48 Citations

    Abstract

    Although single-cell oil (SCO) has been studied for decades, lipid production from lignocellulosic biomass has received substantial attention only in recent years as biofuel research moves toward producing drop-in fuels. This review gives an overview of the feasibility and challenges that exist in realizing microbial lipid production from lignocellulosic biomass in a biorefinery. The aspects covered here include biorefinery technologies, the microbial oil market, oleaginous microbes, lipid accumulation metabolism, strain development, process configurations, lignocellulosic lipid production, technical hurdles, lipid recovery, and technoeconomics. The lignocellulosic SCO-based biorefinery will be feasible only if a combination of low- and high-value lipids are coproduced, while lignin and protein are upgraded to high-value products.

    LanguageEnglish (US)
    Pages43-54
    Number of pages12
    JournalTrends in Biotechnology
    Volume33
    Issue number1
    DOIs
    StatePublished - Jan 1 2015

    Profile

    Lipids
    Oils
    Biomass
    Biofuels
    Lignin
    Lipid Metabolism
    Technology
    Research
    Proteins
    Metabolism
    Recovery

    Keywords

    • Biorefinery
    • Lignocellulosic lipids
    • Microbial lipids
    • Single-cell oil

    ASJC Scopus subject areas

    • Biotechnology
    • Bioengineering

    Cite this

    Jin, M., Slininger, P. J., Dien, B. S., Waghmode, S., Moser, B. R., Orjuela, A., ... Balan, V. (2015). Microbial lipid-based lignocellulosic biorefinery: Feasibility and challenges. Trends in Biotechnology, 33(1), 43-54. DOI: 10.1016/j.tibtech.2014.11.005

    Microbial lipid-based lignocellulosic biorefinery : Feasibility and challenges. / Jin, Mingjie; Slininger, Patricia J.; Dien, Bruce S.; Waghmode, Suresh; Moser, Bryan R.; Orjuela, Andrea; Sousa, Leonardo da Costa; Balan, Venkatesh.

    In: Trends in Biotechnology, Vol. 33, No. 1, 01.01.2015, p. 43-54.

    Research output: Research - peer-reviewArticle

    Jin, M, Slininger, PJ, Dien, BS, Waghmode, S, Moser, BR, Orjuela, A, Sousa, LDC & Balan, V 2015, 'Microbial lipid-based lignocellulosic biorefinery: Feasibility and challenges' Trends in Biotechnology, vol 33, no. 1, pp. 43-54. DOI: 10.1016/j.tibtech.2014.11.005
    Jin M, Slininger PJ, Dien BS, Waghmode S, Moser BR, Orjuela A et al. Microbial lipid-based lignocellulosic biorefinery: Feasibility and challenges. Trends in Biotechnology. 2015 Jan 1;33(1):43-54. Available from, DOI: 10.1016/j.tibtech.2014.11.005
    Jin, Mingjie ; Slininger, Patricia J. ; Dien, Bruce S. ; Waghmode, Suresh ; Moser, Bryan R. ; Orjuela, Andrea ; Sousa, Leonardo da Costa ; Balan, Venkatesh. / Microbial lipid-based lignocellulosic biorefinery : Feasibility and challenges. In: Trends in Biotechnology. 2015 ; Vol. 33, No. 1. pp. 43-54
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