Nanometal-decorated exfoliated graphite nanoplatelet based glucose biosensors with high sensitivity and fast response

Research output: Contribution to journalArticle

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Abstract

We report the novel fabrication of a highly sensitive, selective, fast responding, and affordable amperometric glucose biosensor using exfoliated graphite nanoplatelets (xGnPs) decorated with Pt and Pd nanoparticles. Nafion was used to solublize metal-decorated graphite nanoplatelets, and a simple cast method with high content organic solvent (85 wt %) was used to prepare the biosensors. The addition of precious metal nanoparticles such as platinum (Pt) and palladium (Pd) to xGnP increased the electroactive area of the electrode and substantially decreased the overpotential in the detection of hydrogen peroxide. The Pt-xGnP glucose biosensor had a sensitivity of 61.5 ± 0.6 μA /(mM · cm2) and gave a linear response up to 20 mM. The response time and detection limit (S/N = 3) were determined to be 2 s and 1 μM, respectively. Therefore, this novel glucose biosensor based on the Pt nanoparticle coated xGnP is among the best reported to date in both sensing performance and production cost. In addition, the effects of metal nanoparticle loading and the particle size on the biosensor performance were systematically investigated.

LanguageEnglish (US)
Pages1825-1832
Number of pages8
JournalACS Nano
Volume2
Issue number9
DOIs
StatePublished - Sep 2008

Profile

Graphite
bioinstrumentation
Biosensors
glucose
Glucose
Platinum
graphite
platinum
sensitivity
nanoparticles
Metal nanoparticles
Palladium
palladium
Nanoparticles
production costs
Precious metals
noble metals
hydrogen peroxide
Hydrogen peroxide
metals

Keywords

  • Exfoliated graphite nanoplatelets
  • Glucose biosensor
  • Metal nanoparticles
  • Nafion

ASJC Scopus subject areas

  • Engineering(all)
  • Materials Science(all)
  • Physics and Astronomy(all)

Cite this

Nanometal-decorated exfoliated graphite nanoplatelet based glucose biosensors with high sensitivity and fast response. / Lu, Jue; Do, Inhwan; Drzal, Lawrence T.; Worden, Robert M.; Lee, Ilsoon.

In: ACS Nano, Vol. 2, No. 9, 09.2008, p. 1825-1832.

Research output: Contribution to journalArticle

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